Display options
Cite
Cinel I, Dellinger RP. Current treatment of severe sepsis. Curr Infect Dis Rep. 2006;8(5):358-65doi: 10.1007/s11908-006-0046-0.
Cinel, I., & Dellinger, R. P. (2006). Current treatment of severe sepsis. Current infectious disease reports, 8(5), 358-65. https://doi.org/10.1007/s11908-006-0046-0
Cinel, Ismail, and Dellinger, R Phillip. "Current treatment of severe sepsis." Current infectious disease reports vol. 8,5 (2006): 358-65. doi: https://doi.org/10.1007/s11908-006-0046-0
Cinel I, Dellinger RP. Current treatment of severe sepsis. Curr Infect Dis Rep. 2006 Sep;8(5):358-65. doi: 10.1007/s11908-006-0046-0. PMID: 16934194.
Copy Download .nbib Format: NLM
Share it on

Curr Infect Dis Rep. 2006 Sep;8(5):358-65. doi: 10.1007/s11908-006-0046-0.

Current treatment of severe sepsis.

Current infectious disease reports

Ismail Cinel, R Phillip Dellinger

Affiliations

  1. Section of Critical Care Medicine, Cooper University Hospital, One Cooper Plaza, 393 Dorrance, Camden, NJ 08103, USA. [email protected]

PMID: 16934194 DOI: 10.1007/s11908-006-0046-0

Abstract

The treatment of severe sepsis includes three essential principles: eradication of the inciting infection using source control measures and empiric antibiotics, hemodynamic resuscitation of hypoperfusion to avoid acute life-threatening organ dysfunction, and sustained support of organ system dysfunction using interventions that minimize organ injury. Therapy can be divided into immediate steps taken to stabilize the patient, followed by more definitive therapeutic intervention. The evidence for best clinical practice for resuscitation, management of infection, and intensive care unit supportive care has recently been synthesized by the Surviving Sepsis Campaign and published as evidence-based guidelines for the management of severe sepsis and septic shock.

References

  1. JAMA. 2002 Aug 21;288(7):862-71 - PubMed
  2. J Antimicrob Chemother. 2003 Jun;51(6):1431-4 - PubMed
  3. Intensive Care Med. 2002 Sep;28(9):1208-17 - PubMed
  4. Intensive Care Med. 2004 Mar;30(3):388-94 - PubMed
  5. J Antimicrob Chemother. 2004 Feb;53(2):345-55 - PubMed
  6. Crit Care Med. 2005 Oct;33(10):2194-201 - PubMed
  7. J Biol Chem. 2001 Apr 6;276(14):11199-203 - PubMed
  8. Lancet. 2002 Nov 2;360(9343):1395-6 - PubMed
  9. Curr Opin Crit Care. 2006 Feb;12(1):13-8 - PubMed
  10. Crit Care Med. 2004 Sep;32(9):1825-31 - PubMed
  11. JAMA. 2001 Oct 17;286(15):1869-78 - PubMed
  12. Crit Care Med. 2006 Mar;34(3):612-6 - PubMed
  13. BMJ. 2004 Aug 28;329(7464):480 - PubMed
  14. Clin Infect Dis. 2004 Jan 15;38(2):284-8 - PubMed
  15. Crit Care Med. 2006 Feb;34(2):403-8 - PubMed
  16. Crit Care Med. 2003 Mar;31(3):946-55 - PubMed
  17. Lancet. 2005 Jan 1-7;365(9453):53-9 - PubMed
  18. J Clin Endocrinol Metab. 2003 Mar;88(3):1082-8 - PubMed
  19. Mayo Clin Proc. 2004 Aug;79(8):992-1000 - PubMed
  20. Crit Care Med. 2005 May;33(5):925-9 - PubMed
  21. Blood. 2000 Mar 1;95(5):1680-6 - PubMed
  22. N Engl J Med. 1998 Feb 5;338(6):347-54 - PubMed
  23. Crit Care Med. 2006 Feb;34(2):530-1 - PubMed
  24. Annu Rev Microbiol. 2002;56:657-75 - PubMed
  25. Infect Dis Clin North Am. 1999 Jun;13(2):495-509 - PubMed
  26. JAMA. 2003 Jul 9;290(2):238-47 - PubMed
  27. Crit Care Med. 2005 Apr;33(4):780-6 - PubMed
  28. Chest. 2006 Feb;129(2):225-32 - PubMed
  29. Crit Care Med. 2004 Sep;32(9):1817-24 - PubMed
  30. N Engl J Med. 1994 Jun 16;330(24):1717-22 - PubMed
  31. Chest. 1987 Dec;92(6):1032-6 - PubMed
  32. N Engl J Med. 2000 May 4;342(18):1301-8 - PubMed
  33. Crit Care Med. 2004 Mar;32(3):858-73 - PubMed
  34. Crit Care Med. 2003 Mar;31(3):834-40 - PubMed
  35. Crit Care Med. 2004 Nov;32(11 Suppl):S455-65 - PubMed
  36. N Engl J Med. 2001 Mar 8;344(10 ):699-709 - PubMed
  37. Am J Respir Crit Care Med. 2002 Jul 1;166(1):98-104 - PubMed
  38. N Engl J Med. 2005 Sep 29;353(13):1332-41 - PubMed
  39. J Antimicrob Chemother. 1996 Nov;38(5):865-9 - PubMed
  40. Crit Care Med. 1995 Aug;23(8):1430-9 - PubMed
  41. N Engl J Med. 2001 Nov 8;345(19):1359-67 - PubMed
  42. Clin Infect Dis. 2003 Jan 1;36(1):53-9 - PubMed
  43. N Engl J Med. 2006 Feb 2;354(5):449-61 - PubMed
  44. Crit Care Med. 2006 Jan;34(1):1-7 - PubMed
  45. N Engl J Med. 2001 Nov 8;345(19):1368-77 - PubMed
  46. Crit Care Med. 2004 Nov;32(11 Suppl):S495-512 - PubMed
  47. Crit Care Med. 2004 Jan;32(1):137-43 - PubMed
  48. Crit Care Med. 2003 Dec;31(12):2742-51 - PubMed
  49. N Engl J Med. 2004 May 27;350(22):2247-56 - PubMed
  50. Crit Care Med. 2005 May;33(5):1119-22 - PubMed
  51. Lancet Infect Dis. 2005 Apr;5(4):209-18 - PubMed
  52. Clin Infect Dis. 2005 Feb 1;40(3):374-80 - PubMed
  53. N Engl J Med. 2002 Dec 19;347(25):2020-9 - PubMed
  54. Ann Intern Med. 2004 Jul 6;141(1):47-56 - PubMed
  55. Crit Care. 2004 Dec;8(6):462-8 - PubMed
  56. Anesthesiology. 2002 Mar;96(3):576-82 - PubMed
  57. Crit Care Med. 2005 Oct;33(10 ):2266-77 - PubMed
  58. Crit Care Med. 2006 Jan;34(1):8-14 - PubMed
  59. Am J Respir Crit Care Med. 2005 Dec 1;172(11):1358-9 - PubMed
  60. J Clin Invest. 2005 Aug;115(8):2277-86 - PubMed
  61. Crit Care Med. 2006 Jun;34(6):1589-96 - PubMed

Publication Types