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Int J Hyperthermia. 2006 Nov;22(7):607-12. doi: 10.1080/02656730600968684.

A new local ablation for solid malignant tumours: anti-tumour effect of hyperthermal and electrochemical therapy on transplantable mouse cancer.

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

Lei Xie, Caijun Sun

Affiliations

  1. Department of Head and Neck Surgery, Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, PR China.

PMID: 17079217 DOI: 10.1080/02656730600968684

Abstract

PURPOSE: Hyperthermia induced by electrothermal needle (ETN) and electrochemical therapy (ECT) were combined (HECT) and the anti-tumor effect was evaluated.

METHODS: Mice with Sarcoma180 were randomized into four different treatment groups: Control, ECT alone, Hyperthermia alone and HECT.

RESULTS: The tumours in the HECT group were completely destroyed and they did not recur within a period of 10 days after treatment. However, tumour recurrence was found in six mice in the Hyperthermia group and five mice in the ECT group.

CONCLUSION: The HECT is a potentially effective way to treat solid malignant tumours.

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