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Langley CH, Shrimpton AE, Yamazaki T, et al. Naturally occurring variation in the restriction map of the amy region of Drosophila melanogaster. Genetics. 1988;119(3):619-29doi: 10.1093/genetics/119.3.619.
Langley, C. H., Shrimpton, A. E., Yamazaki, T., Miyashita, N., Matsuo, Y., & Aquadro, C. F. (1988). Naturally occurring variation in the restriction map of the amy region of Drosophila melanogaster. Genetics, 119(3), 619-29. https://doi.org/10.1093/genetics/119.3.619
Langley, C H, et al. "Naturally occurring variation in the restriction map of the amy region of Drosophila melanogaster." Genetics vol. 119,3 (1988): 619-29. doi: https://doi.org/10.1093/genetics/119.3.619
Langley CH, Shrimpton AE, Yamazaki T, Miyashita N, Matsuo Y, Aquadro CF. Naturally occurring variation in the restriction map of the amy region of Drosophila melanogaster. Genetics. 1988 Jul;119(3):619-29. doi: 10.1093/genetics/119.3.619. PMID: 17246437; PMCID: PMC1203447.
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Genetics. 1988 Jul;119(3):619-29. doi: 10.1093/genetics/119.3.619.

Naturally occurring variation in the restriction map of the amy region of Drosophila melanogaster.

Genetics

C H Langley, A E Shrimpton, T Yamazaki, N Miyashita, Y Matsuo, C F Aquadro

Affiliations

  1. Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709.

PMID: 17246437 PMCID: PMC1203447 DOI: 10.1093/genetics/119.3.619

Abstract

The restriction maps of 85 alleles of the Amy region of Drosophila melanogaster from natural populations were surveyed. A subset of these were also scored for allozyme phenotype and adult enzyme activity of alpha-amylase. Large insertions were found in 12% of the alleles in a 15-kb region surrounding the two transcriptional units of the duplicated Amy locus. The low frequencies at which each of these large insertions were found are consistent with earlier reports of variation in other loci. Four small deletions were found in the region 5' to the Amy genes. Each was also rare in the population. Restriction site variation provided an estimate of per nucleotide heterozygosity of 0.006. Several statistically significant linkage disequilibria were observed between four polymorphic restriction sites and the allozymes. Adult alpha-amylase activity was correlated with the allozymes and with the polymorphism at one restriction site close to the transcriptional units.

References

  1. Proc Natl Acad Sci U S A. 1986 Jan;83(2):427-31 - PubMed
  2. Genetics. 1985 Jun;110(2):299-312 - PubMed
  3. Genetics. 1986 Dec;114(4):1165-90 - PubMed
  4. Genetics. 1987 Jan;115(1):129-40 - PubMed
  5. Genet Res. 1987 Feb;49(1):31-41 - PubMed
  6. Proc Natl Acad Sci U S A. 1987 Jan;84(1):174-8 - PubMed
  7. Isozymes Curr Top Biol Med Res. 1987;14:229-66 - PubMed
  8. Mol Biol Evol. 1988 Jan;5(1):30-40 - PubMed
  9. Biochem Genet. 1986 Jun;24(5-6):415-33 - PubMed
  10. Nucleic Acids Res. 1986 Jul 11;14(13):5337-52 - PubMed
  11. Nucleic Acids Res. 1986 Nov 11;14(21):8399-411 - PubMed
  12. Genetics. 1986 Sep;114(1):93-110 - PubMed
  13. Genome. 1987 Jun;29(3):510-5 - PubMed
  14. Genetics. 1985 Jun;110(2):313-24 - PubMed
  15. Proc Natl Acad Sci U S A. 1983 Sep;80(17):5350-4 - PubMed
  16. Proc Natl Acad Sci U S A. 1983 Aug;80(16):5017-21 - PubMed
  17. Proc Natl Acad Sci U S A. 1980 Feb;77(2):1091-5 - PubMed
  18. Proc Natl Acad Sci U S A. 1981 Jun;78(6):3748-50 - PubMed
  19. J Mol Biol. 1981 Jul 5;149(3):319-36 - PubMed
  20. Cell. 1984 Feb;36(2):469-81 - PubMed
  21. Genetics. 1981 Jan;97(1):145-63 - PubMed
  22. Proc Natl Acad Sci U S A. 1982 Sep;79(18):5631-5 - PubMed
  23. Genetics. 1982 Apr;100(4):711-9 - PubMed
  24. Genetics. 1981 Sep;99(1):151-6 - PubMed
  25. Genetics. 1982 Nov;102(3):437-53 - PubMed
  26. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4446-50 - PubMed
  27. Genetics. 1977 Jun;86(2 Pt. 1):447-54 - PubMed
  28. Proc Natl Acad Sci U S A. 1979 Oct;76(10):5269-73 - PubMed
  29. Genetics. 1974 Nov;78(3):921-36 - PubMed
  30. Genetics. 1974 Aug;77(4):771-93 - PubMed
  31. Nature. 1972 Aug 25;238(5365):453-4 - PubMed
  32. Proc Natl Acad Sci U S A. 1980 Feb;77(2):1073-7 - PubMed
  33. Genetics. 1984 Sep;108(1):223-35 - PubMed
  34. Genetics. 1983 Jul;104(3):473-83 - PubMed
  35. Genetics. 1982 Jun;101(2):235-56 - PubMed
  36. Genetics. 1986 Nov;114(3):943-54 - PubMed
  37. Genetics. 1986 Nov;114(3):875-84 - PubMed
  38. Genetics. 1959 Jan;44(1):34-42 - PubMed
  39. Genetics. 1959 Nov;44(6):1243-56 - PubMed
  40. J Biol Chem. 1951 Nov;193(1):265-75 - PubMed
  41. Mol Biol Evol. 1987 Nov;4(6):651-63 - PubMed
  42. Genetics. 1986 Nov;114(3):731-52 - PubMed
  43. Int Rev Cytol. 1985;93:281-326 - PubMed

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