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Nielsen JT, Chapman VM. Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse. Genetics. 1977;87(2):319-25doi: 10.1093/genetics/87.2.319.
Nielsen, J. T., & Chapman, V. M. (1977). Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse. Genetics, 87(2), 319-25. https://doi.org/10.1093/genetics/87.2.319
Nielsen, J T, and Chapman, V M. "Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse." Genetics vol. 87,2 (1977): 319-25. doi: https://doi.org/10.1093/genetics/87.2.319
Nielsen JT, Chapman VM. Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse. Genetics. 1977 Oct;87(2):319-25. doi: 10.1093/genetics/87.2.319. PMID: 17248765; PMCID: PMC1213743.
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Genetics. 1977 Oct;87(2):319-25. doi: 10.1093/genetics/87.2.319.

Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse.

Genetics

J T Nielsen, V M Chapman

Affiliations

  1. Institute of Genetics, University of Aarhus, Aarhus, Denmark.

PMID: 17248765 PMCID: PMC1213743 DOI: 10.1093/genetics/87.2.319

Abstract

Electrophoretic variation for X-chromosome-linked phosphoglycerate kinase (PGK-1) has been found as a polymorphism in feral mice in Denmark. Males from feral sampling or from a variety of genetic crosses have only a single-banded phenotype of the variant PGK-1A type or of the PGK-1B type commonly found among inbred mice. By contrast, three phenotypes were observed among females; two homozygous single-banded types and a heterozygous double-banded type. The X-chromosome linkage of the Pgk-1 locus was determined from the mode of inheritance in F(1) and backcross generations and confirmed by the linkage of Pgk-1 and the X-linked markers Hq, Ta and Mo. Pgk-1 showed 29/122 recombinations with Hq, 5/185 with Ta and 0/108 recombinants with Mo. Based on these recombination data, a gene order of Hq-Ta-Pgk-1-Mo is suggested.

References

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