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Zhang S, Zeng X, Xu X, et al. Application of microdialysis technique in the traditional chinese medicine. Conf Proc IEEE Eng Med Biol Soc. 2005;2005:7726-9doi: 10.1109/IEMBS.2005.1616303.
Zhang, S., Zeng, X., Xu, X., & Zheng, X. (2005). Application of microdialysis technique in the traditional chinese medicine. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 20057726-9. https://doi.org/10.1109/IEMBS.2005.1616303
Zhang, Shaomin, et al. "Application of microdialysis technique in the traditional chinese medicine." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference vol. 2005 (2005): 7726-9. doi: https://doi.org/10.1109/IEMBS.2005.1616303
Zhang S, Zeng X, Xu X, Zheng X. Application of microdialysis technique in the traditional chinese medicine. Conf Proc IEEE Eng Med Biol Soc. 2005;2005:7726-9. doi: 10.1109/IEMBS.2005.1616303. PMID: 17282072.
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Conf Proc IEEE Eng Med Biol Soc. 2005;2005:7726-9. doi: 10.1109/IEMBS.2005.1616303.

Application of microdialysis technique in the traditional chinese medicine.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Shaomin Zhang, Xianghui Zeng, Xiaohong Xu, Xiaoxiang Zheng

Affiliations

  1. Key Laboratory of Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou, 310027, P.R.China; Department of Biomedical Engineering, Zhejiang University, Hangzhou, 310027, P.R.China.

PMID: 17282072 DOI: 10.1109/IEMBS.2005.1616303

Abstract

The concentration of extracellular neurotransmitters can be dynamically measured by in vivo microdialysis. This technique can apply to quantitatively evaluating the beneficial effects of Traditional Chinese Medicine (TCM). In the present study, the protective effects of Puerarin (Pur) on cerebral injuries evoked by ischemia/reperfusion was supported by a decrease of extracellular amino acids, especially glutamate (Glu), which were monitored by microdialysis combined with HPLC throughout the experiments. It suggested that, in addition to being a versatile and practical method in neuroscience, the microdialysis technique would play an important role in assessing and screening the effects of TCM.

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