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Hanna D, Gross B, Lempicki E, et al. Detection of Vesicular Stomatitis Virus using a Capacitive Immunosensor. Conf Proc IEEE Eng Med Biol Soc. 2005;2006:534-7doi: 10.1109/IEMBS.2005.1616466.
Hanna, D., Gross, B., Lempicki, E., Oakley, B., Kandlikar, S., & Stryker, G. (2005). Detection of Vesicular Stomatitis Virus using a Capacitive Immunosensor. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2006534-7. https://doi.org/10.1109/IEMBS.2005.1616466
Hanna, Darrin, et al. "Detection of Vesicular Stomatitis Virus using a Capacitive Immunosensor." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference vol. 2006 (2005): 534-7. doi: https://doi.org/10.1109/IEMBS.2005.1616466
Hanna D, Gross B, Lempicki E, Oakley B, Kandlikar S, Stryker G. Detection of Vesicular Stomatitis Virus using a Capacitive Immunosensor. Conf Proc IEEE Eng Med Biol Soc. 2005;2006:534-7. doi: 10.1109/IEMBS.2005.1616466. PMID: 17282235.
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Conf Proc IEEE Eng Med Biol Soc. 2005;2006:534-7. doi: 10.1109/IEMBS.2005.1616466.

Detection of Vesicular Stomatitis Virus using a Capacitive Immunosensor.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Darrin Hanna, Brooks Gross, Elizabeth Lempicki, Barbara Oakley, Sachin Kandlikar, Gabrielle Stryker

Affiliations

  1. School of Engineering and Computer Science, Oakland University, Rochester, Michigan, USA.

PMID: 17282235 DOI: 10.1109/IEMBS.2005.1616466

Abstract

This paper describes the detection of Vesicular Stomatitis Virus using a novel capacitive immunosensor technology, whereby the respective antibodies for the antigens were used as a means for chemical detection on separate sensors. Devices were fabricated using standard etching and metal plating techniques, followed by immobilization of antibodies. Detection of antigen was performed by measuring voltage change due to changes in capacitance as antigen bound to the antibody surface. Capacitance changes were detected upon binding of specific antigen to the surface. This rugged, prototype device detected VSV down to the 2 pg/ml range.

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