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Ann Readapt Med Phys. 2007 Jul;50(6):450-4, 445-9. doi: 10.1016/j.annrmp.2007.03.010. Epub 2007 Mar 28.

Physical activity in the management of cancer-related fatigue induced by oncological treatments.

Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique

[Article in French]
J L Labourey

Affiliations

  1. Service d'oncologie médicale [Medical Oncology Department], CHU Dupuytren [Dupuytren Teaching Hospital], 2, avenue Martin-Luther-King, 87042 Limoges cedex, France. [email protected]

PMID: 17399841 DOI: 10.1016/j.annrmp.2007.03.010

Abstract

OBJECTIVE: We aimed to review the literature on physical activity in the management of cancer-related fatigue.

MATERIALS AND METHODS: A search of PubMed for English- or French-language articles using the keywords fatigue, cancer, exercise, physical activity, sport, randomized, and controlled.

RESULTS: We found reports of 11 randomized or controlled studies, all of them in English. Most involved small numbers of patients. Four of the studies reported that physical exercise had an effect on the fatigue: three a positive effect and one a negative effect. One of these four studies was carried out in patients still undergoing treatment (hormone therapy). Of the three post-treatment studies, the two finding positive effect involved breast cancer patients quite a while after the end of treatment (chemotherapy and/or radiotherapy), whereas the study finding a negative effect involved patients 1 month after treatment, all with chemotherapy.

CONCLUSION: Physical activity appears to be a good way of combating fatigue induced by various cancer therapies. However, many questions remain, which highlights the need for randomized studies with sufficient numbers of patients.

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