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Procaccini M, Campisi G, Bufo P, et al. Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. Head Face Med. 2007;3:25doi: 10.1186/1746-160X-3-25.
Procaccini, M., Campisi, G., Bufo, P., Compilato, D., Massaccesi, C., Catassi, C., & Lo Muzio, L. (2007). Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. Head & face medicine, 325. https://doi.org/10.1186/1746-160X-3-25
Procaccini, Maurizio, et al. "Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region." Head & face medicine vol. 3 (2007): 25. doi: https://doi.org/10.1186/1746-160X-3-25
Procaccini M, Campisi G, Bufo P, Compilato D, Massaccesi C, Catassi C, Lo Muzio L. Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. Head Face Med. 2007 May 30;3:25. doi: 10.1186/1746-160X-3-25. PMID: 17537244; PMCID: PMC1891285.
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Head Face Med. 2007 May 30;3:25. doi: 10.1186/1746-160X-3-25.

Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region.

Head & face medicine

Maurizio Procaccini, Giuseppina Campisi, Pantaleo Bufo, Domenico Compilato, Claudia Massaccesi, Carlo Catassi, Lorenzo Lo Muzio

Affiliations

  1. Istituto di Scienze Odontostomatologiche, Università Politecnica delle Marche, Italy. [email protected]

PMID: 17537244 PMCID: PMC1891285 DOI: 10.1186/1746-160X-3-25

Abstract

BACKGROUND: A close correlation between celiac disease (CD) and oral lesions has been reported. The aim of this case-control study was to assess prevalence of enamel hypoplasia, recurrent aphthous stomatitis (RAS), dermatitis herpetiformis and atrophic glossitis in an Italian cohort of patients with CD.

METHODS: Fifty patients with CD and fifty healthy subjects (age range: 3-25 years), matched for age, gender and geographical area, were evaluated by a single trained examiner. Diagnosis of oral diseases was based on typical medical history and clinical features. Histopathological analysis was performed when needed. Adequate univariate statistical analysis was performed.

RESULTS: Enamel hypoplasia was observed in 26% cases vs 16% in controls (p > 0.2; OR = 1.8446; 95% CI = 0.6886: 4.9414). Frequency of RAS in the CD group was significantly higher (36% vs 12%; p = 0.0091; OR = 4.125; 95% CI = 1.4725: 11.552) in CD group than that in controls (36% vs 12%). Four cases of atrophic glossitis and 1 of dermatitis herpetiformis were found in CD patients vs 1 and none, respectively, among controls.

CONCLUSION: The prevalence of enamel hypoplasia was not higher in the study population than in the control group. RAS was significantly more frequent in patients with CD.

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