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J Med Case Rep. 2007 Jul 25;1:56. doi: 10.1186/1752-1947-1-56.

Severe hypercalcaemia and lymphoma in an HTLV-1 positive Jamaican woman: a case report.

Journal of medical case reports

Veronica Lyell, Elham Khatamzas, Theresa Allain

Affiliations

  1. Department of Care of the Elderly, Southmead Hospital, Bristol, UK. [email protected].

PMID: 17651486 PMCID: PMC1950877 DOI: 10.1186/1752-1947-1-56

Abstract

Human T cell lymphotrophic virus type-1 infection is endemic in the Afro-Caribbean community in Britain, with carriage rates of about 3%. Although there is a long latency, carriers have a 1-5% chance of developing adult T cell leukaemia/lymphoma, a condition frequently complicated by marked and refractory hypercalcaemia, and with a poor prognosis. We present the case of an elderly Jamaican woman with severe hypercalcaemia and a raised PTHrP who was found to have lymphoma and was positive for HTLV-1.

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