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Trends Biotechnol. 2007 Sep;25(9):395-400. doi: 10.1016/j.tibtech.2007.07.008. Epub 2007 Aug 03.

Proteomics of filamentous fungi.

Trends in biotechnology

Yonghyun Kim, M P Nandakumar, Mark R Marten

Affiliations

  1. Department of Chemical and Biochemical Engineering, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.

PMID: 17681627 DOI: 10.1016/j.tibtech.2007.07.008

Abstract

Proteomic analysis, defined here as the global assessment of cellular proteins expressed in a particular biological state, is a powerful tool that can provide a systematic understanding of events at the molecular level. Proteomic studies of filamentous fungi have only recently begun to appear in the literature, despite the prevalence of these organisms in the biotechnology industry, and their importance as both human and plant pathogens. Here, we review recent publications that have used a proteomic approach to develop a better understanding of filamentous fungi, highlighting sample preparation methods and whole-cell cytoplasmic proteomics, as well as subproteomics of cell envelope, mitochondrial and secreted proteins.

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