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Lipids. 1968 Sep;3(5):411-6. doi: 10.1007/BF02531279.

The incorporation of(14)C-glycerol into different species of diglycerides and triglycerides in rat liver slices.

Lipids

E E Hill, W E Lands, S P Slakey

Affiliations

  1. Department of Biological Chemistry, The University of Michigan, 48104, Ann Arbor, Michigan.

PMID: 17805819 DOI: 10.1007/BF02531279

Abstract

The relative rates of de novo synthesis of species of diglycerides and triglycerides from(14)C-glycerol were examined in rat liver slices. Diglycerides containing one or two double bonds per molecule and triglycerides containing four or more double bonds per molecule represented 70% and 60% respectively of the newly synthesized diglycerides and triglycerides. The newly synthesized triglycerides were more unsaturated than the endogenous triglycerides. Our results suggest that a nonrandom synthesis of species of diglycerides occurred followed by an almost random utilization of the various diglyceride species for the biosynthesis of triglycerides.

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