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Stage KB, Middelboe T, Stage TB, et al. Depression in COPD--management and quality of life considerations. Int J Chron Obstruct Pulmon Dis. 2006;1(3):315-20doi: 10.2147/copd.2006.1.3.315.
Stage, K. B., Middelboe, T., Stage, T. B., & Sørensen, C. H. (2006). Depression in COPD--management and quality of life considerations. International journal of chronic obstructive pulmonary disease, 1(3), 315-20. https://doi.org/10.2147/copd.2006.1.3.315
Stage, Kurt B, et al. "Depression in COPD--management and quality of life considerations." International journal of chronic obstructive pulmonary disease vol. 1,3 (2006): 315-20. doi: https://doi.org/10.2147/copd.2006.1.3.315
Stage KB, Middelboe T, Stage TB, Sørensen CH. Depression in COPD--management and quality of life considerations. Int J Chron Obstruct Pulmon Dis. 2006;1(3):315-20. doi: 10.2147/copd.2006.1.3.315. PMID: 18046868; PMCID: PMC2707161.
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Int J Chron Obstruct Pulmon Dis. 2006;1(3):315-20. doi: 10.2147/copd.2006.1.3.315.

Depression in COPD--management and quality of life considerations.

International journal of chronic obstructive pulmonary disease

Kurt B Stage, Thomas Middelboe, Tore B Stage, Claus H Sørensen

Affiliations

  1. Department of Psychiatry, Odense University Hospital, Denmark. [email protected]

PMID: 18046868 PMCID: PMC2707161 DOI: 10.2147/copd.2006.1.3.315

Abstract

Depression is common in COPD patients. Around 40% are affected by severe depressive symptoms or clinical depression. It is not easy to diagnose depression in COPD patients because of overlapping symptoms between COPD and depression. However, the six-item Hamilton Depression Subscale appears to be a useful screening tool. Quality of life is strongly impaired in COPD patients and patients' quality of life emerges to be more correlated with the presence of depressive symptoms than with the severity of COPD. Nortriptyline and imipramine are effective in the treatment of depression, but little is known about the usefulness of newer antidepressants. In patients with milder depression, pulmonary rehabilitation as well as cognitive-behavioral therapy are effective. Little is known about the long-term outcome in COPD patients with co-morbid depression. Preliminary data suggest that co-morbid depression may be an independent protector for mortality.

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