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Song KS, Chang SH, Suh JS. [Two cases of heparin-induced thrombocytopenia diagnosed by particle gel immunoassay.]. Korean J Lab Med. 2006;26(5):334-7doi: 10.3343/kjlm.2006.26.5.334.
Song, K. S., Chang, S. H., & Suh, J. S. (2006). [Two cases of heparin-induced thrombocytopenia diagnosed by particle gel immunoassay.]. The Korean journal of laboratory medicine, 26(5), 334-7. https://doi.org/10.3343/kjlm.2006.26.5.334
Song, Kyu Sub, et al. "[Two cases of heparin-induced thrombocytopenia diagnosed by particle gel immunoassay.]." The Korean journal of laboratory medicine vol. 26,5 (2006): 334-7. doi: https://doi.org/10.3343/kjlm.2006.26.5.334
Song KS, Chang SH, Suh JS. [Two cases of heparin-induced thrombocytopenia diagnosed by particle gel immunoassay.]. Korean J Lab Med. 2006 Oct;26(5):334-7. doi: 10.3343/kjlm.2006.26.5.334. Korean. PMID: 18156747.
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Korean J Lab Med. 2006 Oct;26(5):334-7. doi: 10.3343/kjlm.2006.26.5.334.

[Two cases of heparin-induced thrombocytopenia diagnosed by particle gel immunoassay.].

The Korean journal of laboratory medicine

[Article in Korean]
Kyu Sub Song, Soon Hee Chang, Jang Soo Suh

Affiliations

  1. Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea. [email protected].

PMID: 18156747 DOI: 10.3343/kjlm.2006.26.5.334

Abstract

Heparin-induced thrombocytopenia (HIT) is a serious complication of heparin therapy. It represents initially as thrombocytopenia and is associated with venous or arterial thrombosis. It has been reported that platelet factor 4/heparin complex antibody plays an important role in the pathogenesis of HIT. Patients on hemodialysis have a high risk of developing HIT because heparin is administrated in hemodialysis as anticoagulant. Thrombocytopenia usually occurs 5 to 10 days after the onset of administration, but occasionally, it may occur rapidly in patients who have preformed antibodies from recent heparin use. We report here 2 cases of HIT with platelet factor 4-heparin reactive antibody in hemodialysis patients.

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