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Fähnrich J, Castelano C, Sturzenegger E, et al. Postoperative Analgesie mit Buprenorphin : Eine vergleichende Studie zwischen epiduraler, patientenkontrollierter intravenöser und konventioneller subkutaner applikation. [Postoperative analgesia with buprenorphine : A comparative study of epidural, patient-controlled intravenous and conventional subcutaneous administration.]. Schmerz. 1990;4(4):201-6doi: 10.1007/BF02527904.
Fähnrich, J., Castelano, C., Sturzenegger, E., Stoll, B., Uehlinger, P., & Geroulanos, S. (1990). Postoperative Analgesie mit Buprenorphin : Eine vergleichende Studie zwischen epiduraler, patientenkontrollierter intravenöser und konventioneller subkutaner applikation. [Postoperative analgesia with buprenorphine : A comparative study of epidural, patient-controlled intravenous and conventional subcutaneous administration.]. Schmerz (Berlin, Germany), 4(4), 201-6. https://doi.org/10.1007/BF02527904
Fähnrich, J, et al. "Postoperative Analgesie mit Buprenorphin : Eine vergleichende Studie zwischen epiduraler, patientenkontrollierter intravenöser und konventioneller subkutaner applikation." [Postoperative analgesia with buprenorphine : A comparative study of epidural, patient-controlled intravenous and conventional subcutaneous administration.]. Schmerz (Berlin, Germany) vol. 4,4 (1990): 201-6. doi: https://doi.org/10.1007/BF02527904
Fähnrich J, Castelano C, Sturzenegger E, Stoll B, Uehlinger P, Geroulanos S. Postoperative Analgesie mit Buprenorphin : Eine vergleichende Studie zwischen epiduraler, patientenkontrollierter intravenöser und konventioneller subkutaner applikation. [Postoperative analgesia with buprenorphine : A comparative study of epidural, patient-controlled intravenous and conventional subcutaneous administration.]. Schmerz. 1990 Dec;4(4):201-6. doi: 10.1007/BF02527904. German. PMID: 18415237.
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Schmerz. 1990 Dec;4(4):201-6. doi: 10.1007/BF02527904.

[Postoperative analgesia with buprenorphine : A comparative study of epidural, patient-controlled intravenous and conventional subcutaneous administration.].

Schmerz (Berlin, Germany)

[Article in German]
J Fähnrich, C Castelano, E Sturzenegger, B Stoll, P Uehlinger, S Geroulanos

Affiliations

  1. Institut für Anaesthesiologie, Universitätsspital, Zürich, Schweiz.

PMID: 18415237 DOI: 10.1007/BF02527904

Abstract

Thirty patients who had undergone elective anterolateral thoracotomy were studied in the surgical intensive care unit to compare the analgesic effectiveness of i.v. self-administered buprenorphine (group A) with that of epidural administration (group B) and of s.c. administration by a nurse of 0.3 mg buprenorphine every 3-4 h (group C, controls). Every 2 h the patients were asked to record their subjektive pain level as a percentage on an analogue scale: zero was to be used for no pain and 100% for the most severe pain they could imagine. the mean of all analogue scores for pain in the first 36 h was 19.4+/-3.1 for group A; 18.4+/-2.3 for group B and 42.0+/-7.4 for group C (P<0.025). When the mean scores were referred to time, it seemed that groups A and B suffered a little more pain immediately after the operation; however, after 4 h the mean scores for these groups were far lower than that for the control group. The amount of buprenorphine used during the first 36 h was 0.036+/-0.006 mg/h per m(2) in group A, 0.021+/-0.002 mg/h per m(2) in group B and 0.038+0.004 mg/h in the control group. The mean interval between two injections was 9.47+/-1.4 h in group A, 2.47+0.5 h in group B, and 5.18+0.7 h in group C. It can be concluded that, at least in patients in an intensive care unit, scheduled administration of pain killers is unacceptable now. The self-administration device has shown the possibility of on-demand i.v. administration, which is no more dangerous than scheduled s.c. administration. Nurses should be instructed to provide analgesic medication on demand. Epidural administration of buprenorphine is superior to self-administration in terms of the amount of drugs used and the dosing intervals. In the quality of analgesia epidural administration and self-administration are equal and superior to the control procedure.

References

  1. Br Med J (Clin Res Ed). 1983 Feb 26;286(6366):680-2 - PubMed
  2. Arch Gen Psychiatry. 1978 Apr;35(4):501-16 - PubMed
  3. Anasth Intensivther Notfallmed. 1981 Dec;16(6):333-9 - PubMed
  4. Ann Surg. 1982 Jun;195(6):700-5 - PubMed
  5. Br J Anaesth. 1983 Sep;55(9):922 - PubMed
  6. Anesthesiology. 1984 Sep;61(3):276-310 - PubMed
  7. Anasth Intensivther Notfallmed. 1984 Oct;19(5):226-30 - PubMed
  8. Anaesth Intensive Care. 1984 May;12(2):179 - PubMed

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