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HPB (Oxford). 2001;3(2):183-6. doi: 10.1080/136518201317077224.

Cystadenoma of the liver without mesenchymal stroma in a female following hormonal therapy for acne.

HPB : the official journal of the International Hepato Pancreato Biliary Association

E Dixon, F R Sutherland, K Burak, G McKinnon, G May

Affiliations

  1. Department of Surgery, University of Calgary, Calgary, Alberta, Canada.

PMID: 18332923 PMCID: PMC2020801 DOI: 10.1080/136518201317077224

Abstract

BACKGROUND: Liver cystadenomas are relatively rare tumours that can be difficult to diagnose; treatment entails complete surgical extirpation either by either anatomical resection or enucleation.

CASE OUTLINE: A 19-year-old woman presented with acute onset of abdominal pain and was found to have a multilocular giant liver cyst.The cyst was percutaneously drained; CEA and CA 19-9 tumour markers were elevated in this cyst fluid: CEA 96 microg/L, CAI9-9 37 550 kU/L. The cyst was completely enucleated and has not recurred. Pathological examination confirmed a cystadenoma without mesenchymal stroma, and tumour oestrogen and progesterone receptors were negative.

DISCUSSION: This is the fourth report of a liver cystadenoma without mesenchymal stroma in a female and the first to document elevated cyst fluid tumour markers. This case also illustrates the possible relationship between hormonal therapy and tumour growth.

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