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Chohan ZH, Praveen M, Ghaffar A. Structural and Biological Behaviour of Co(II), Cu(II) and Ni(II) Metal Complexes of Some Amino Acid Derived Schiff-Bases. Met Based Drugs. 1997;4(5):267-72doi: 10.1155/MBD.1997.267.
Chohan, Z. H., Praveen, M., & Ghaffar, A. (1997). Structural and Biological Behaviour of Co(II), Cu(II) and Ni(II) Metal Complexes of Some Amino Acid Derived Schiff-Bases. Metal-based drugs, 4(5), 267-72. https://doi.org/10.1155/MBD.1997.267
Chohan, Z H, et al. "Structural and Biological Behaviour of Co(II), Cu(II) and Ni(II) Metal Complexes of Some Amino Acid Derived Schiff-Bases." Metal-based drugs vol. 4,5 (1997): 267-72. doi: https://doi.org/10.1155/MBD.1997.267
Chohan ZH, Praveen M, Ghaffar A. Structural and Biological Behaviour of Co(II), Cu(II) and Ni(II) Metal Complexes of Some Amino Acid Derived Schiff-Bases. Met Based Drugs. 1997;4(5):267-72. doi: 10.1155/MBD.1997.267. PMID: 18475798; PMCID: PMC2365081.
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Met Based Drugs. 1997;4(5):267-72. doi: 10.1155/MBD.1997.267.

Structural and Biological Behaviour of Co(II), Cu(II) and Ni(II) Metal Complexes of Some Amino Acid Derived Schiff-Bases.

Metal-based drugs

Z H Chohan, M Praveen, A Ghaffar

Affiliations

  1. Department of Chemistry University of Aberdeen Scotland Old Aberdeen AB9 2UE UK.

PMID: 18475798 PMCID: PMC2365081 DOI: 10.1155/MBD.1997.267

Abstract

Biologically active tridentate amino acid (Alanine, Glycine & Tyrosine) derived Schiff-bases and their Co(II), Cu(II) & Ni(II) complexes have been synthesised and characterised on the basis of their conductance and magnetic measurements, elemental analysis and (13)C-NMR, (1)H-NMR, IR and electronic spectral data. These Schiff-bases and their complexes have been evaluated for their antibacterial activity against bacterial species such as Staphylococcus aureus, Escherichia coli, Klebsiella pneumonae, Proteus vulgarus and Pseudomonas aeruginosa and this activity data show the metal complexes to be more antibacterial than the Schiff-bases against one or more bacterial species.

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