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Chakravorty I, Oldfield WL, Gómez CM. Rapidly progressive Bronchiolitis Obliterans Organising Pneumonia presenting with pneumothorax, persistent air leak, acute respiratory distress syndrome and multi-organ dysfunction: a case report. J Med Case Rep. 2008;2:145doi: 10.1186/1752-1947-2-145.
Chakravorty, I., Oldfield, W. L., & Gómez, C. M. (2008). Rapidly progressive Bronchiolitis Obliterans Organising Pneumonia presenting with pneumothorax, persistent air leak, acute respiratory distress syndrome and multi-organ dysfunction: a case report. Journal of medical case reports, 2145. https://doi.org/10.1186/1752-1947-2-145
Chakravorty, Indranil, et al. "Rapidly progressive Bronchiolitis Obliterans Organising Pneumonia presenting with pneumothorax, persistent air leak, acute respiratory distress syndrome and multi-organ dysfunction: a case report." Journal of medical case reports vol. 2 (2008): 145. doi: https://doi.org/10.1186/1752-1947-2-145
Chakravorty I, Oldfield WL, Gómez CM. Rapidly progressive Bronchiolitis Obliterans Organising Pneumonia presenting with pneumothorax, persistent air leak, acute respiratory distress syndrome and multi-organ dysfunction: a case report. J Med Case Rep. 2008 May 06;2:145. doi: 10.1186/1752-1947-2-145. PMID: 18460192; PMCID: PMC2397425.
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J Med Case Rep. 2008 May 06;2:145. doi: 10.1186/1752-1947-2-145.

Rapidly progressive Bronchiolitis Obliterans Organising Pneumonia presenting with pneumothorax, persistent air leak, acute respiratory distress syndrome and multi-organ dysfunction: a case report.

Journal of medical case reports

Indranil Chakravorty, William L G Oldfield, Carlos M H Gómez

Affiliations

  1. Department of Respiratory Medicine, Lister Hospital, Beds & Herts Postgraduate Medical School, Stevenage, UK. [email protected]

PMID: 18460192 PMCID: PMC2397425 DOI: 10.1186/1752-1947-2-145

Abstract

INTRODUCTION: Bronchiolitis Obliterans Organising Pneumonia (BOOP) may often present initially as a recurrent spontaneous pneumothorax and then develop multi-system complications.

CASE PRESENTATION: A 17-year-old boy presented with a pneumothorax, which developed into rapidly progressive Bronchiolitis Obliterans Organising Pneumonia (BOOP). He developed multi-organ dysfunction (including adult respiratory distress syndrome, oliguric renal failure, acute coronary syndrome, cardiac failure and a right atrial thrombus) which necessitated prolonged intensive care. Diagnosis was confirmed on open lung biopsy and he responded well to treatment with corticosteroids.

CONCLUSION: BOOP is exquisitely sensitive to oral corticosteroids but if the diagnosis is not considered in such patients and appropriate treatment instituted early, BOOP may often lead to prolonged hospital admission with considerable morbidity.

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