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Danner H, Neureiter M, Madzingaidzo L, et al. Bacillus stearothermophilus for thermophilic production of L-lactic acid. Appl Biochem Biotechnol. 1998;70:895-903doi: 10.1007/BF02920200.
Danner, H., Neureiter, M., Madzingaidzo, L., Gartner, M., & Braun, R. (1998). Bacillus stearothermophilus for thermophilic production of L-lactic acid. Applied biochemistry and biotechnology, 70895-903. https://doi.org/10.1007/BF02920200
Danner, H, et al. "Bacillus stearothermophilus for thermophilic production of L-lactic acid." Applied biochemistry and biotechnology vol. 70 (1998): 895-903. doi: https://doi.org/10.1007/BF02920200
Danner H, Neureiter M, Madzingaidzo L, Gartner M, Braun R. Bacillus stearothermophilus for thermophilic production of L-lactic acid. Appl Biochem Biotechnol. 1998;70:895-903. doi: 10.1007/BF02920200. PMID: 18576053.
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Appl Biochem Biotechnol. 1998;70:895-903. doi: 10.1007/BF02920200.

Bacillus stearothermophilus for thermophilic production of L-lactic acid.

Applied biochemistry and biotechnology

H Danner, M Neureiter, L Madzingaidzo, M Gartner, R Braun

Affiliations

  1. Institute for Agrobiotechnology Tulln (IFA-Tulln), Department for Environmental Biotechnology, Konrad Lorenz Str. 20, A-3430 Tulln, Austria. [email protected]

PMID: 18576053 DOI: 10.1007/BF02920200

Abstract

A process for the continuous production of high purity L-lactic acid in a membrane bioreactor at 65 degrees C has been developed. Two different Bacillus stearothermophilus strains have been tested in batch experiments. Lactic acid yields are between 60 and more than 95% of theoretical yields. The amounts of ethanol, acetate, and formate formed varied between 0 and 0.4, 0 and 0.1, and 0 and 0.5, respectively (mol/mol glucose). All byproducts are valuable and may be separated easily by rectification of the fermentation broth. Complete cell retention enables high volumetric productivity (5 g/Lh), and a minimum of growth supplements. The high temperature of 65 degrees C allows the autoselective fermentation without problems with contamination.

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