Display options
Cite
Goltzman D, Hendy GN, Banville D. Parathyroid hormone-like peptide: molecular characterization and biological properties. Trends Endocrinol Metab. 1989;1(1):39-44doi: 10.1016/1043-2760(89)90029-5.
Goltzman, D., Hendy, G. N., & Banville, D. (1989). Parathyroid hormone-like peptide: molecular characterization and biological properties. Trends in endocrinology and metabolism: TEM, 1(1), 39-44. https://doi.org/10.1016/1043-2760(89)90029-5
Goltzman, D, et al. "Parathyroid hormone-like peptide: molecular characterization and biological properties." Trends in endocrinology and metabolism: TEM vol. 1,1 (1989): 39-44. doi: https://doi.org/10.1016/1043-2760(89)90029-5
Goltzman D, Hendy GN, Banville D. Parathyroid hormone-like peptide: molecular characterization and biological properties. Trends Endocrinol Metab. 1989 Sep-Oct;1(1):39-44. doi: 10.1016/1043-2760(89)90029-5. PMID: 18411086.
Copy Download .nbib Format: NLM
Share it on

Trends Endocrinol Metab. 1989 Sep-Oct;1(1):39-44. doi: 10.1016/1043-2760(89)90029-5.

Parathyroid hormone-like peptide: molecular characterization and biological properties.

Trends in endocrinology and metabolism: TEM

D Goltzman, G N Hendy, D Banville

Affiliations

  1. Departments of Physiology and Medicine, McGill University, Montreal, Canada.

PMID: 18411086 DOI: 10.1016/1043-2760(89)90029-5

Abstract

Parathyroid hormone-like peptide (PLP) is a newly discovered novel peptide that interacts with renal and osseous parathyroid hormone (PTH) receptors through its amino-terminal sequence, which is homologous with PTH. Human PLP is the product of a complex single-copy gene, existing in several isoforms which result from alternative exon usage. The peptide was implicated as a causal agent in the hypercalcemia associated with a variety of malignancies, but it may also modulate calcium homeostasis in some normal physiological states and mediate cellular growth or differentiation.

Publication Types