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Biotechnol Bioeng. 1985 Jul;27(7):984-95. doi: 10.1002/bit.260270709.

Mathematical modelling of growth and substrate conversion of Zymomonas mobilis at 30 and 35 degrees C.

Biotechnology and bioengineering

I M Jöbses, G T Egberts, A van Baalen, J A Roels

Affiliations

  1. Laboratory of Bioengineering, Department of Chemistry and Chemical Engineering, Delft University of Technology, Delft, The Netherlands.

PMID: 18553768 DOI: 10.1002/bit.260270709

Abstract

Zymomonas mobilis was grown in continuous cultures at 30 and 35 degrees C. The specific substrate consumption rates at 35 degrees C were higher than those at 30 degrees C. An unstructured mathematical model based on the linear equation for substrate consumption provided a statistically adequate description for cultures grown at 35 degrees C but not for cultures grown at 30 degrees C. A structured two-compartment model described growth and substrate consumption well at both temperatures. Some theoretical and practical aspects of the two-compartment model are discussed.

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