Display options
Cite
Strohmann C, Gessner VH. A precoordination complex of 1,2,3-trimethyl-1,3,5-triazacyclohexane with tert-butyllithium as key intermediate in its methylene group deprotonation. Chem Asian J. 2008;3(11):1929-34doi: 10.1002/asia.200800213.
Strohmann, C., & Gessner, V. H. (2008). A precoordination complex of 1,2,3-trimethyl-1,3,5-triazacyclohexane with tert-butyllithium as key intermediate in its methylene group deprotonation. Chemistry, an Asian journal, 3(11), 1929-34. https://doi.org/10.1002/asia.200800213
Strohmann, Carsten, and Gessner, Viktoria H. "A precoordination complex of 1,2,3-trimethyl-1,3,5-triazacyclohexane with tert-butyllithium as key intermediate in its methylene group deprotonation." Chemistry, an Asian journal vol. 3,11 (2008): 1929-34. doi: https://doi.org/10.1002/asia.200800213
Strohmann C, Gessner VH. A precoordination complex of 1,2,3-trimethyl-1,3,5-triazacyclohexane with tert-butyllithium as key intermediate in its methylene group deprotonation. Chem Asian J. 2008 Nov 13;3(11):1929-34. doi: 10.1002/asia.200800213. PMID: 18752226.
Copy Download .nbib Format: NLM
Share it on

Chem Asian J. 2008 Nov 13;3(11):1929-34. doi: 10.1002/asia.200800213.

A precoordination complex of 1,2,3-trimethyl-1,3,5-triazacyclohexane with tert-butyllithium as key intermediate in its methylene group deprotonation.

Chemistry, an Asian journal

Carsten Strohmann, Viktoria H Gessner

Affiliations

  1. Institut für Anorganische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany. [email protected]

PMID: 18752226 DOI: 10.1002/asia.200800213

Abstract

Alpha-lithiated tertiary methylamines are important building blocks in all fields of chemistry, such as for the synthesis of new ligand or catalyst systems. However, the access to these compounds is still limited and the reaction mechanism, in general, not fully understood. We present herein X-ray diffraction analyses of organolithium compounds with 1,2,3-trimethyl-1,3,5-triazacyclohexane (1), such as a precoordination adduct of tert-butyllithium, [(tBuLi)(3)C(6)H(15)N(3)], which represents a potential intermediate of the lithiation of the methylene group of this ligand. By means of molecular structures and computational studies, the regioselectivity of this deprotonation reaction can be understood. Furthermore, the tBuLi adduct gives a hint to an alternative deaggregation process of organolithium compounds.

Publication Types