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Samaras P, Pfammatter T, Pestalozzi BC. Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report. Int Semin Surg Oncol. 2008;5:17doi: 10.1186/1477-7800-5-17.
Samaras, P., Pfammatter, T., & Pestalozzi, B. C. (2008). Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report. International seminars in surgical oncology : ISSO, 517. https://doi.org/10.1186/1477-7800-5-17
Samaras, Panagiotis, et al. "Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report." International seminars in surgical oncology : ISSO vol. 5 (2008): 17. doi: https://doi.org/10.1186/1477-7800-5-17
Samaras P, Pfammatter T, Pestalozzi BC. Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report. Int Semin Surg Oncol. 2008 Jul 11;5:17. doi: 10.1186/1477-7800-5-17. PMID: 18620556; PMCID: PMC2478651.
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Int Semin Surg Oncol. 2008 Jul 11;5:17. doi: 10.1186/1477-7800-5-17.

Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report.

International seminars in surgical oncology : ISSO

Panagiotis Samaras, Thomas Pfammatter, Bernhard C Pestalozzi

Affiliations

  1. Department of Oncology, University Hospital Zurich, Zurich, Switzerland. [email protected].

PMID: 18620556 PMCID: PMC2478651 DOI: 10.1186/1477-7800-5-17

Abstract

Pseudoaneurysms of the hepatic artery are a rare complication in patients with primary or secondary liver tumors treated with intra-arterial chemotherapy. We present two patients who developed this complication after placement of a catheter system into the gastroduodenal artery and initiation of regional chemotherapy with floxuridine. Diagnosis was made after symptomatic bleeding occurred, necessitating emergency angiography with coil embolization. Pseudoaneurysms usually occur after mechanical damage of the vessel wall, but the chemical toxicity of floxuridine may add to the development of vascular impairment.

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