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Biotechnol Bioeng. 1991 Aug 20;38(5):439-46. doi: 10.1002/bit.260380502.

Diffusion in gels containing immobilized cells: a critical review.

Biotechnology and bioengineering

B A Westrin, A Axelsson

Affiliations

  1. Department of Chemical Engineering 1, Lund University S-221 00 Lund, Sweden.

PMID: 18604802 DOI: 10.1002/bit.260380502

Abstract

Eleven experimental investigation of diffusion in gels containing immobilized cells are reviewed. The experimental data, which quantitatively express the diffusion coefficient as a function of the cell concentration, are compared with a number of well-known equations developed for mass transfer in heterogeneous media. Based on this comparison, a procedure for the theoretical prediction of effective diffusion coefficients in cell-containing gels is recommended.

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