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J Clin Neurosci. 1995 Apr;2(2):171-6. doi: 10.1016/0967-5868(95)90013-6.

Rapidly progressive Whipple's disease of the central nervous system.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

R Niekrash, C McLean, A Kaye, R Hjorth, P Desmond, V Sinicaks, M Gonzales

Affiliations

  1. Department of Neurosurgery, The Melbourne Neuroscience, Centre, Parkville, Victoria, Australia.

PMID: 18638806 DOI: 10.1016/0967-5868(95)90013-6

Abstract

We describe a patient with rapidly progressive Whipple's disease confined to the central nervous system (CNS). The diagnosis was made pre-mortem following stereotactic and open brain biopsis and confirmed at autopsy. Despite appropriate antibiotic treatment, the disease ran a fulminant course to death after nine weeks.

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