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Talanta. 1979 Jan;26(1):63-4. doi: 10.1016/0039-9140(79)80158-7.

A colorimetric method for the determination of nitrazepam.

Talanta

N M Sanghavin, N G Jivani

Affiliations

  1. Department of Chemical Technology, University of Bombay, Matunga Road, Bombay 400019, India.

PMID: 18962378 DOI: 10.1016/0039-9140(79)80158-7

Abstract

A simple colorimetric method for the determination of nitrazepam is described. Nitrazepam dissolved in ethyl alcohol (95%) produces a yellow anion on addition of aqueous sodium hydroxide, and this is measured spectrophotometrically. The method has been applied to pharmaceutical formulations containing nitrazepam.

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