Display options
Cite
Belal F, Rizk M, Ibrahiem F, et al. Spectrophotometric determination of benzothiadiazines in dosage forms. Talanta. 1986;33(2):170-2doi: 10.1016/0039-9140(86)80036-4.
Belal, F., Rizk, M., Ibrahiem, F., & El-Din, M. S. (1986). Spectrophotometric determination of benzothiadiazines in dosage forms. Talanta, 33(2), 170-2. https://doi.org/10.1016/0039-9140(86)80036-4
Belal, F, et al. "Spectrophotometric determination of benzothiadiazines in dosage forms." Talanta vol. 33,2 (1986): 170-2. doi: https://doi.org/10.1016/0039-9140(86)80036-4
Belal F, Rizk M, Ibrahiem F, El-Din MS. Spectrophotometric determination of benzothiadiazines in dosage forms. Talanta. 1986 Feb;33(2):170-2. doi: 10.1016/0039-9140(86)80036-4. PMID: 18964056.
Copy Download .nbib Format: NLM
Share it on

Talanta. 1986 Feb;33(2):170-2. doi: 10.1016/0039-9140(86)80036-4.

Spectrophotometric determination of benzothiadiazines in dosage forms.

Talanta

F Belal, M Rizk, F Ibrahiem, M S El-Din

Affiliations

  1. Department of Analytical Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt.

PMID: 18964056 DOI: 10.1016/0039-9140(86)80036-4

Abstract

The analytical utility of ethyl acetoacetate for the spectrophotometric determination of benzothiadiazine diuretics has been studied. The procedure developed is based on coupling of the diazotized drugs with the reagent, which possesses an active methylene group. The stoichiometry of the reaction is presented. The nominal recovery of the drugs from pharmaceutical preparations ranges from 97.6 +/- 0.7 to 102.3 +/- 0.3%. The suggested method is simple, sensitive and applicable to unit dose analysis.

Publication Types