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Panzarini SR, Souza V, Holland R, et al. Association of calcium hydroxide and metronidazole in the treatment of dog's teeth with chronic periapical lesion. J Appl Oral Sci. 2006;14(5):334-40doi: 10.1590/s1678-77572006000500007.
Panzarini, S. R., Souza, V., Holland, R., & Dezan Júnior, E. (2006). Association of calcium hydroxide and metronidazole in the treatment of dog's teeth with chronic periapical lesion. Journal of applied oral science : revista FOB, 14(5), 334-40. https://doi.org/10.1590/s1678-77572006000500007
Panzarini, Sônia Regina, et al. "Association of calcium hydroxide and metronidazole in the treatment of dog's teeth with chronic periapical lesion." Journal of applied oral science : revista FOB vol. 14,5 (2006): 334-40. doi: https://doi.org/10.1590/s1678-77572006000500007
Panzarini SR, Souza V, Holland R, Dezan Júnior E. Association of calcium hydroxide and metronidazole in the treatment of dog's teeth with chronic periapical lesion. J Appl Oral Sci. 2006 Oct;14(5):334-40. doi: 10.1590/s1678-77572006000500007. PMID: 19089054; PMCID: PMC4327224.
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J Appl Oral Sci. 2006 Oct;14(5):334-40. doi: 10.1590/s1678-77572006000500007.

Association of calcium hydroxide and metronidazole in the treatment of dog's teeth with chronic periapical lesion.

Journal of applied oral science : revista FOB

Sônia Regina Panzarini, Valdir Souza, Roberto Holland, Eloi Dezan Júnior

Affiliations

  1. Department of Surgery and Integrated Clinics, Dental School of Araçatuba - UNESP - São Paulo State University, Araçatuba, São Paulo, Brazil. [email protected]

PMID: 19089054 PMCID: PMC4327224 DOI: 10.1590/s1678-77572006000500007

Abstract

UNLABELLED: One of the primary objectives of endodontic treatment of teeth with pulp necrosis is the elimination of microorganisms from the root canal system, as effectively as possible, especially in cases with chronic periapical lesions.

AIM: The purpose of this study was to analyze the response of the periapical tissue of dogs' teeth with chronic periapical lesions to endodontic treatment performed with utilization of metronidazole, calcium hydroxide, and an association of both as root canal dressings.

METHODOLOGY: Forty root canals were submitted to pulpectomy and the root canals were kept exposed to the oral environment for 6 months. Then, they were submitted to biomechanical preparation and divided into 4 study groups with 10 specimens: group I - no root canal dressing; group II - calcium hydroxide; group III - metronidazole; group IV - calcium hydroxide associated to metronidazole. After 15 days, the root canals were filled with Fill Canal sealer. After 90 days, the animals were killed and the specimens processed for histological analysis.

RESULTS: Calcium hydroxide dressing provided a significantly better outcome compared to other experimental groups (alpha = 0.01). Also, the results of the association of metronidazole and calcium hydroxide were similar to those observed for the metronidazole group. The worst results were obtained by the no root canal dressing group.

CONCLUSION: The use of metronidazole alone or associated with Calcium hydroxide, did not improve periapical healing when compared to Calcium hydroxide dressing.

References

  1. Scand J Dent Res. 1981 Aug;89(4):321-8 - PubMed
  2. J Endod. 1990 Dec;16(12):580-8 - PubMed
  3. Endod Dent Traumatol. 1990 Jun;6(3):129-36 - PubMed
  4. Oral Surg Oral Med Oral Pathol. 1987 Mar;63(3):366-70 - PubMed
  5. Braz Dent J. 2002;13(1):17-22 - PubMed
  6. J Endod. 2005 Jun;31(6):439-43 - PubMed
  7. Endod Dent Traumatol. 1987 Apr;3(2):58-63 - PubMed
  8. Oral Surg Oral Med Oral Pathol. 1983 Mar;55(3):307-12 - PubMed
  9. Int Endod J. 1992 Mar;25(2):97-106 - PubMed
  10. Endod Dent Traumatol. 1985 Oct;1(5):170-5 - PubMed
  11. Oral Surg Oral Med Oral Pathol. 1970 Apr;29(4):613-9 - PubMed
  12. Oral Surg Oral Med Oral Pathol. 1994 Oct;78(4):522-30 - PubMed
  13. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Sep;94(3):281-93 - PubMed
  14. Endod Dent Traumatol. 1993 Feb;9(1):8-12 - PubMed
  15. J Endod. 1994 Apr;20(4):169-72 - PubMed
  16. Arch Oral Biol. 1991;36(2):117-28 - PubMed
  17. J Endod. 1975 Jan;1(1):19-21 - PubMed
  18. Endod Dent Traumatol. 1987 Apr;3(2):86-90 - PubMed
  19. J Endod. 1993 Feb;19(2):76-8 - PubMed
  20. J Dent Res. 1982 Feb;61(2):435-8 - PubMed
  21. J Endod. 1997 Mar;23(3):167-9 - PubMed
  22. J Endod. 1982 Oct;8(10):444-7 - PubMed

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