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Conti F, Valerio MC, Zbilut JP, et al. Will systems biology offer new holistic paradigms to life sciences?. Syst Synth Biol. 2008;1(4):161-5doi: 10.1007/s11693-008-9016-1.
Conti, F., Valerio, M. C., Zbilut, J. P., & Giuliani, A. (2007). Will systems biology offer new holistic paradigms to life sciences?. Systems and synthetic biology, 1(4), 161-5. https://doi.org/10.1007/s11693-008-9016-1
Conti, Filippo, et al. "Will systems biology offer new holistic paradigms to life sciences?." Systems and synthetic biology vol. 1,4 (2007): 161-5. doi: https://doi.org/10.1007/s11693-008-9016-1
Conti F, Valerio MC, Zbilut JP, Giuliani A. Will systems biology offer new holistic paradigms to life sciences?. Syst Synth Biol. 2007 Dec;1(4):161-5. doi: 10.1007/s11693-008-9016-1. Epub 2008 May 30. PMID: 19003440; PMCID: PMC2553325.
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Syst Synth Biol. 2007 Dec;1(4):161-5. doi: 10.1007/s11693-008-9016-1. Epub 2008 May 30.

Will systems biology offer new holistic paradigms to life sciences?.

Systems and synthetic biology

Filippo Conti, Maria Cristina Valerio, Joseph P Zbilut, Alessandro Giuliani

Affiliations

  1. Chemistry Department, University of Rome, 'La Sapienza', Rome, Italy.

PMID: 19003440 PMCID: PMC2553325 DOI: 10.1007/s11693-008-9016-1

Abstract

A biological system, like any complex system, blends stochastic and deterministic features, displaying properties of both. In a certain sense, this blend is exactly what we perceive as the "essence of complexity" given we tend to consider as non-complex both an ideal gas (fully stochastic and understandable at the statistical level in the thermodynamic limit of a huge number of particles) and a frictionless pendulum (fully deterministic relative to its motion). In this commentary we make the statement that systems biology will have a relevant impact on nowadays biology if (and only if) will be able to capture the essential character of this blend that in our opinion is the generation of globally ordered collective modes supported by locally stochastic atomisms.

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