Display options
Share it on

Evid Based Complement Alternat Med. 2011;2011:792975. doi: 10.1093/ecam/nen080. Epub 2010 Oct 20.

Delayed Effect of Acupuncture Treatment in OA of the Knee: A Blinded, Randomized, Controlled Trial.

Evidence-based complementary and alternative medicine : eCAM

Ehud Miller, Yair Maimon, Yishai Rosenblatt, Anat Mendler, Avi Hasner, Adi Barad, Hagay Amir, Shmuel Dekel, Shahar Lev-Ari

Affiliations

  1. Unit of Complementary Medicine, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

PMID: 19124552 PMCID: PMC3137589 DOI: 10.1093/ecam/nen080

Abstract

To assess the efficacy in providing improved function and pain relief by administering 8 weeks of acupuncture as adjunctive therapy to standard care in elderly patients with OA of the knee. This randomized, controlled, blinded trial was conducted on 55 patients with OA of the knee. Forty-one patients completed the study (26 females, 15 males, mean age ± SD 71.7 ± 8.6 years). Patients were randomly divided into an intervention group that received biweekly acupuncture treatment (n = 28) and a control group that received sham acupuncture (n = 27), both in addition to standard therapy, for example, NSAIDS, cyclooxygenase-2 inhibitors, acetaminophen, intra-articular hyaluronic acid and steroid injections. Primary outcomes measures were changes in the Knee Society Score (KSS) knee score and in KSS function and pain ratings at therapy onset, at 8 weeks (closure of study) and at 12 weeks (1 month after last treatment). Secondary outcomes were patient satisfaction and validity of sham acupuncture. There was significant improvement in all three scores in both groups after 8 and 12 weeks compared with baseline (P < .05). Significant differences between the intervention and control groups in the KSS knee score (P = .036) was apparent only after 12 weeks. Patient satisfaction was higher in the intervention group. Adjunctive acupuncture treatment seems to provide added improvement to standard care in elderly patients with OA of the knee. Future research should determine the optimal duration of acupuncture treatment in the context of OA.

References

  1. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2670-3 - PubMed
  2. J Rheumatol Suppl. 2000 Oct;60:6-8 - PubMed
  3. Life Sci. 1980 Feb 25;26(8):631-8 - PubMed
  4. Ann Intern Med. 2004 Dec 21;141(12):901-10 - PubMed
  5. Pain. 2000 Mar;85(1-2):169-82 - PubMed
  6. Am J Chin Med. 2005;33(1):157-64 - PubMed
  7. Arch Phys Med Rehabil. 1993 Jan;74(1):54-60 - PubMed
  8. Lancet. 2005 Jul 9-15;366(9480):136-43 - PubMed
  9. J Bone Joint Surg Am. 2001 Aug;83(8):1149-56 - PubMed
  10. Eur J Appl Physiol. 2005 Aug;94(5-6):633-40 - PubMed
  11. Acupunct Med. 2001 Jun;19(1):15-8 - PubMed
  12. Rheumatology (Oxford). 2007 Mar;46(3):384-90 - PubMed
  13. Acta Orthop Scand. 1997 Feb;68(1):41-5 - PubMed
  14. J Altern Complement Med. 2005 Aug;11(4):653-61 - PubMed
  15. Adv Data. 2004 May 27;(343):1-19 - PubMed
  16. Arch Otolaryngol Head Neck Surg. 1999 May;125(5):567-72 - PubMed
  17. Anesth Analg. 2004 May;98(5):1359-64, table of contents - PubMed
  18. Semin Arthritis Rheum. 1990 Dec;20(3 Suppl 1):42-50 - PubMed
  19. Pain. 1986 Oct;27(1):101-115 - PubMed
  20. Curr Opin Rheumatol. 2002 Sep;14(5):573-7 - PubMed
  21. Clin Orthop Relat Res. 1989 Nov;(248):13-4 - PubMed
  22. Hum Brain Mapp. 2005 Mar;24(3):193-205 - PubMed
  23. Acta Chir Orthop Traumatol Cech. 2007 Oct;74(5):332-5 - PubMed
  24. Acupunct Electrother Res. 2002;27(2):107-17 - PubMed
  25. Knee. 2008 Jun;15(3):217-21 - PubMed
  26. Neuroimage. 2005 Sep;27(3):479-96 - PubMed
  27. Arthritis Rheum. 2000 Sep;43(9):1905-15 - PubMed
  28. Schmerz. 1994 Mar;8(1):37-42 - PubMed

Publication Types