Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2056-60.

[AMWFA method applied to research on changes of essential components and extractive ratioes of herbal pair Cinnamomum cassia and Poria cocos].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Article in Chinese]
Zheng Xiang, Xian-Qin Wang, Xiao-Min Yu, Tao Wei, Yan-Xia Li

PMID: 19160782

Abstract

Gas chromatography/mass spectrometry, chemometric resolution method-Alternative movingwindow factor analysis that were proposed recently and the Kovats retention index were used to analyze the essential components of herbal pair Cinnamomum cassia Presl and Poria cocos (CCP-PC) and compare them with those of single herbal Cinnamomum cassia Presl (CCP). 46 and 42 essential components in essential oil of CCP and CCP-PC have been identified individually. Results shows that the number of essential components of CCP and CCP-PC were almost the same, but extractive ratioes of them have changed significantly, some of them were increased obviously, most of them were declined notably instead and even several ingredients of CCP-PC were disappeared due to CCP PC's interaction probably. The main pharmacodynamic ingredients of CCP-PC, 3-phenyl-2-propenal and Cinnamaldehyde were obviously higher contents than that of single CCP. It suggested that there exist certain interactions of the chemical ingredients in compound medicine rather than their sum effect of single medicines. There is a litter difference in quality and quantity between single medicines and pair medicines, so the application of pair medicines can expand single medicine's adaptive disease and has a good clinical referenced valuation.

Substances

• Drugs, Chinese Herbal

MeSH terms

• Cinnamomum aromaticum / chemistry
• Drugs, Chinese Herbal / chemistry
• Gas Chromatography-Mass Spectrometry
• Poria / chemistry

Publication Types

• English Abstract
• Journal Article