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Atzmony L, Saar N, Chundadze T, et al. Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report. J Med Case Rep. 2008;2:385doi: 10.1186/1752-1947-2-385.
Atzmony, L., Saar, N., Chundadze, T., Arbel, Y., Justo, D., & Mashav, N. (2008). Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report. Journal of medical case reports, 2385. https://doi.org/10.1186/1752-1947-2-385
Atzmony, Lihi, et al. "Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report." Journal of medical case reports vol. 2 (2008): 385. doi: https://doi.org/10.1186/1752-1947-2-385
Atzmony L, Saar N, Chundadze T, Arbel Y, Justo D, Mashav N. Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report. J Med Case Rep. 2008 Dec 16;2:385. doi: 10.1186/1752-1947-2-385. PMID: 19087249; PMCID: PMC2615038.
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J Med Case Rep. 2008 Dec 16;2:385. doi: 10.1186/1752-1947-2-385.

Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report.

Journal of medical case reports

Lihi Atzmony, Nili Saar, Tamar Chundadze, Yaron Arbel, Dan Justo, Noa Mashav

Affiliations

  1. Department of Internal Medicine D, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel. [email protected]

PMID: 19087249 PMCID: PMC2615038 DOI: 10.1186/1752-1947-2-385

Abstract

INTRODUCTION: Cytomegalovirus-associated thrombosis has rarely been reported in the medical literature, and if so, mainly in immunocompromized patients.

CASE PRESENTATION: We report the case of a 36-year-old Caucasian woman with acute cytomegalovirus infection presenting with spontaneous splenic infarcts. Trans-esophageal echocardiography did not show any vegetations or mural thrombi. The patient was also found to be heterozygous for the Factor V Leiden mutation. Anticoagulation treatment was considered but ruled out since cytomegalovirus was the obvious trigger for thrombosis in this patient. To the best of our knowledge, this is only the third report to date of cytomegalovirus-associated splenic infarcts.

CONCLUSION: This case report serves as additional evidence for the role of cytomegalovirus in thrombosis.

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