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Saudi J Kidney Dis Transpl. 2005 Oct-Dec;16(4):514-9.

Polyomavirus nephropathy.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

Emilio Ramos, Cinthia Drachenberg

Affiliations

  1. Department of Medicine, Division of Nephrology, University of Maryland School of Medicine, Maryland, USA.

PMID: 18202506

Abstract

We have seen the re-emergence of a virus, normally latent in the urinary tract, which becomes activated in renal transplant patients due to potent immunosuppression. Polyomavirus reactivates within the allograft kidney, causing renal dysfunction and graft loss in 40 to70% of patients with overt renal dysfunction and histologically proven Polyomavirus nephropathy. More research and data are needed to further elucidate the pathogenicity of the virus, and to find an effective antiviral agent.

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