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Reznek R. Islet cell tumours. Cancer Imaging. 2003;4(1):1-4doi: 10.1102/1470-7330.2003.0023.
Reznek, R. (2003). Islet cell tumours. Cancer imaging : the official publication of the International Cancer Imaging Society, 4(1), 1-4. https://doi.org/10.1102/1470-7330.2003.0023
Reznek, R. "Islet cell tumours." Cancer imaging : the official publication of the International Cancer Imaging Society vol. 4,1 (2003): 1-4. doi: https://doi.org/10.1102/1470-7330.2003.0023
Reznek R. Islet cell tumours. Cancer Imaging. 2003 Sep 30;4(1):1-4. doi: 10.1102/1470-7330.2003.0023. PMID: 18211851; PMCID: PMC1434518.
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Cancer Imaging. 2003 Sep 30;4(1):1-4. doi: 10.1102/1470-7330.2003.0023.

Islet cell tumours.

Cancer imaging : the official publication of the International Cancer Imaging Society

R Reznek

Affiliations

  1. Academic Department of Diagnostic Radiology St Bartholomew's Hospital, London, UK. [email protected]

PMID: 18211851 PMCID: PMC1434518 DOI: 10.1102/1470-7330.2003.0023

Abstract

Islet cells tumours are a range of rare neoplasms of neuroendocrine origin arising in or close to the pancreas. The normal islet cells of Langerhans in the pancreas contain B-cells (which secrete insulin), A-cells (which secrete glucagon), D-cells (which secrete somatostatin), Dl-cells (which secrete pancreatic polypeptide, PP) and D2-cells (which secrete vasoactive intestinal peptide). The majority (85%) of islet cell tumours secrete one or more of these hormones, or other substances not normally found in the adult pancreas (although often present in the fetal pancreas), notably gastrin.

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