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Arch Gerontol Geriatr. 1990 Jul-Aug;11(1):53-61. doi: 10.1016/0167-4943(90)90056-c.

Heteromorphism of chromosome 1, 9 and 16 homologues in high- and medium-longevity level regions.

Archives of gerontology and geriatrics

S M Kuznetsova, M Y Zaritskaya

Affiliations

  1. Institute of Gerontology AMS U.S.S.R., Vyshgorodskaya 67, 252655, Kiev 114, USSR.

PMID: 15374493 DOI: 10.1016/0167-4943(90)90056-c

Abstract

Regional and age-related peculiarities of chromosomal polymorphism are established as a result of studies in C-band heteromorphism of chromosomes 1, 9 and 16 in the long-lived subjects, their relatives and population groups of the Abkhazian and Ukrainian regions. Heteromorphism frequencies of chromosomes 1 and 9 homologues are high in the Abkhazian as compared with the Ukrainian regions. Age-related differences as to the degree of expression of chromosome 9 C-band heteromorphism found are as follows: in the Abkhazian region the frequency of variants with a high degree of heteromorphism increases with age, while in the Ukrainian region, with a low degree of heteromorphism, it decreases.

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