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Reid ME, Marfoe RA, Mueller AL, et al. A second example of anti-Esa, an antibody to a high-incidence Cromer antigen. Immunohematology. 1996;12(3):112-4
Reid, M. E., Marfoe, R. A., Mueller, A. L., Arndt, P. A., Sausais, L., & Spruell, P. (1996). A second example of anti-Esa, an antibody to a high-incidence Cromer antigen. Immunohematology, 12(3), 112-4.
Reid, M E, et al. "A second example of anti-Esa, an antibody to a high-incidence Cromer antigen." Immunohematology vol. 12,3 (1996): 112-4.
Reid ME, Marfoe RA, Mueller AL, Arndt PA, Sausais L, Spruell P. A second example of anti-Esa, an antibody to a high-incidence Cromer antigen. Immunohematology. 1996;12(3):112-4. PMID: 15387735.
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Immunohematology. 1996;12(3):112-4.

A second example of anti-Esa, an antibody to a high-incidence Cromer antigen.

Immunohematology

M E Reid, R A Marfoe, A L Mueller, P A Arndt, L Sausais, P Spruell

Affiliations

  1. Immunohematology Laboratory, 310 East 67th Street, New York, NY 10021, USA.

PMID: 15387735

Abstract

A blood sample contained an antibody to a high-incidence antigen that reacted with all red blood cells (RBCs) tested by the indirect antiglobulin test (IAT). The antibody reacted with papain-, ficin-, and trypsin-treated RBCs, but not with a-chymotrypsin-treated RBCs. This pattern of reactivity suggested the possibility that the antibody was recognizing an antigen in the Cromer blood group system. Tests against RBCs deficient in decay-accelerating factor (which carries the Cromer antigens) were weakly positive. Tests with antibodies to high-incidence Cromer antigens and with RBCs lacking high-incidence Cromer antigens led to identification of the second example of anti-Esa in an Es(a-) person. The antibody was IgG1 and reacted by the IAT to a titer of 64. The monocyte monolayer assay indicated potential clinical significance of this antibody in relation to transfusion.

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