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Pain Manag Nurs. 2008 Mar;9(1):S22-32. doi: 10.1016/j.pmn.2007.11.003.

Pharmacotherapy for acute pain: implications for practice.

Pain management nursing : official journal of the American Society of Pain Management Nurses

Dina A Krenzischek, Colleen J Dunwoody, Rosemary C Polomano, James P Rathmell

Affiliations

  1. Same-Day Prep/Post-Anesthesia Care Unit, Department of Anesthesia & Critical Care, Department of Surgical Nursing, Johns Hopkins Hospital, Baltimore, Maryland, USA. [email protected]

PMID: 18294591 DOI: 10.1016/j.pmn.2007.11.003

Abstract

Effective treatment of perioperative acute pain requires that information about the patient's goals for pain relief, previous history with analgesics, and type of surgical procedure is used to guide decisions about analgesic regimens. Analgesics are selected based on the location of surgery, degree of anticipated pain, and patient characteristics (such as comorbidities), and routes of administration and dosing schedules are determined to maximize the effectiveness and safety of analgesia while minimizing the potential for adverse events. Pain management therapy is then extended into the postsurgical phase of recovery. To accomplish this, nurses must have a thorough understanding of the pharmacology of analgesics. This article provides useful information for commonly used analgesics, primarily nonsteroidal antiinflammatory drugs (NSAIDs), opioids, and local anesthetics for control of acute postoperative pain.

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