Display options
Cite
Kim H, Kim HI, Johnson PV, et al. Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2. Anal Chem. 2008;80(6):1928-36doi: 10.1021/ac701888e.
Kim, H., Kim, H. I., Johnson, P. V., Beegle, L. W., Beauchamp, J. L., Goddard, W. A., & Kanik, I. (2008). Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2. Analytical chemistry, 80(6), 1928-36. https://doi.org/10.1021/ac701888e
Kim, Hyungjun, et al. "Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2." Analytical chemistry vol. 80,6 (2008): 1928-36. doi: https://doi.org/10.1021/ac701888e
Kim H, Kim HI, Johnson PV, Beegle LW, Beauchamp JL, Goddard WA, Kanik I. Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2. Anal Chem. 2008 Mar 15;80(6):1928-36. doi: 10.1021/ac701888e. Epub 2008 Feb 16. PMID: 18278882.
Copy Download .nbib Format: NLM
Share it on

Anal Chem. 2008 Mar 15;80(6):1928-36. doi: 10.1021/ac701888e. Epub 2008 Feb 16.

Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2.

Analytical chemistry

Hyungjun Kim, Hugh I Kim, Paul V Johnson, Luther W Beegle, J L Beauchamp, William A Goddard, Isik Kanik

Affiliations

  1. Materials and Process Simulation Center, Beckman Institute, California Institute of Technology, Pasadena, California 91125, USA.

PMID: 18278882 DOI: 10.1021/ac701888e

Abstract

A number of tertiary amine and quaternary ammonium cations spanning a mass range of 60-146 amu (trimethylamine, tetramethylammonium, trimethylethylammonium, N,N-dimethylaminoethanol, choline, N,N-dimethylglycine, betaine, acetylcholine, (3-carboxypropyl)trimethylammonium) were investigated using electrospray ionization ion mobility spectrometry. Measured ion mobilities demonstrate a high correlation between mass and mobility in N(2). In addition, identical mobilities within experimental uncertainties are observed for structurally dissimilar ions with similar ion masses. For example, dimethylethylammonium (88 amu) cations and protonated N,N-dimethylaminoethanol cations (90 amu) show identical mobilities (1.93 cm(2) V(-1) s(-1)) though N,N-dimethylaminoethanol contains a hydroxyl functional group while dimethylethylammonium only contains alkyl groups. Computational analysis was performed using the modified trajectory (TJ) method with nonspherical N(2) molecules as the drift gas. The sensitivity of the ammonium cation collision cross sections to the details of the ion-neutral interactions was investigated and compared to other classes of organic molecules (carboxylic acids and abiotic amino acids). The specific charge distribution of the molecular ions in the investigated mass range has an insignificant affect on the collision cross section.

Publication Types