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Earnest CP, Hammar MK, Munsey M, et al. Microencapsulated foods as a functional delivery vehicle for omega-3 fatty acids: a pilot study. J Int Soc Sports Nutr. 2009;6:12doi: 10.1186/1550-2783-6-12.
Earnest, C. P., Hammar, M. K., Munsey, M., Mikus, C. R., David, R. M., Bralley, J. A., & Church, T. S. (2009). Microencapsulated foods as a functional delivery vehicle for omega-3 fatty acids: a pilot study. Journal of the International Society of Sports Nutrition, 612. https://doi.org/10.1186/1550-2783-6-12
Earnest, Conrad P, et al. "Microencapsulated foods as a functional delivery vehicle for omega-3 fatty acids: a pilot study." Journal of the International Society of Sports Nutrition vol. 6 (2009): 12. doi: https://doi.org/10.1186/1550-2783-6-12
Earnest CP, Hammar MK, Munsey M, Mikus CR, David RM, Bralley JA, Church TS. Microencapsulated foods as a functional delivery vehicle for omega-3 fatty acids: a pilot study. J Int Soc Sports Nutr. 2009 May 29;6:12. doi: 10.1186/1550-2783-6-12. PMID: 19480650; PMCID: PMC2694142.
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J Int Soc Sports Nutr. 2009 May 29;6:12. doi: 10.1186/1550-2783-6-12.

Microencapsulated foods as a functional delivery vehicle for omega-3 fatty acids: a pilot study.

Journal of the International Society of Sports Nutrition

Conrad P Earnest, Molly K Hammar, Monica Munsey, Catherine R Mikus, Robert M David, J Alexander Bralley, Timothy S Church

Affiliations

  1. Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA. [email protected].

PMID: 19480650 PMCID: PMC2694142 DOI: 10.1186/1550-2783-6-12

Abstract

It is well established that the ingestion of the omega-3 (N3) fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) positively benefit a variety of health indices. Despite these benefits the actual intake of fish derived N3 is relatively small in the United States. The primary aim of our study was to examine a technology capable of delivering omega-3 fatty acids in common foods via microencapsulation (MicroN3) in young, healthy, active participants who are at low risk for cardiovascular disease. Accordingly, we randomized 20 participants (25.4 +/- 6.2 y; 73.4 +/- 5.1 kg) to receive the double blind delivery of a placebo-matched breakfast meal (~2093 kJ) containing MicroN3 (450-550 mg EPA/DHA) during a 2-week pilot trial. Overall, we observed no differences in overall dietary macronutrient intake other than the N3 delivery during our treatment regimen. Post-test ANOVA analysis showed a significant elevation in mean (SE) plasma DHA (91.18 +/- 9.3 vs. 125.58 +/- 11.3 umol/L; P < 0.05) and a reduction in triacylglycerols (89.89 +/- 12.8 vs. 80.78 +/- 10.4 mg/dL; P < 0.05) accompanying the MicroN3 treatment that was significantly different from placebo (P < 0.05). In post study interviews, participants reported that the ingested food was well-tolerated, contained no fish taste, odor or gastrointestinal distress accompanying treatment. The use of MicroN3 foods provides a novel delivery system for the delivery of essential fatty acids. Our study demonstrates that MicroN3 foods promote the absorption of essential N3, demonstrate bioactivity within 2 weeks of ingestion and are well tolerated in young, active participants who are at low risk for cardiovascular disease.

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