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Steinbigler P, Haberl R, Vogel J, et al. Funktionelle Spätpotentialanalyse im 24-Stunden-Langzeit-EKG. [Functional late potential analysis in the 24-hour electrocardiogram]. Herzschrittmacherther Elektrophysiol. 1997;8(4):245-54doi: 10.1007/BF03042615.
Steinbigler, P., Haberl, R., Vogel, J., Schmücking, I., Spiegl, A., & Steinbeck, G. (1997). Funktionelle Spätpotentialanalyse im 24-Stunden-Langzeit-EKG. [Functional late potential analysis in the 24-hour electrocardiogram]. Herzschrittmachertherapie & Elektrophysiologie, 8(4), 245-54. https://doi.org/10.1007/BF03042615
Steinbigler, P, et al. "Funktionelle Spätpotentialanalyse im 24-Stunden-Langzeit-EKG." [Functional late potential analysis in the 24-hour electrocardiogram]. Herzschrittmachertherapie & Elektrophysiologie vol. 8,4 (1997): 245-54. doi: https://doi.org/10.1007/BF03042615
Steinbigler P, Haberl R, Vogel J, Schmücking I, Spiegl A, Steinbeck G. Funktionelle Spätpotentialanalyse im 24-Stunden-Langzeit-EKG. [Functional late potential analysis in the 24-hour electrocardiogram]. Herzschrittmacherther Elektrophysiol. 1997 Dec;8(4):245-54. doi: 10.1007/BF03042615. German. PMID: 19484327.
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Herzschrittmacherther Elektrophysiol. 1997 Dec;8(4):245-54. doi: 10.1007/BF03042615.

[Functional late potential analysis in the 24-hour electrocardiogram].

Herzschrittmachertherapie & Elektrophysiologie

[Article in German]
P Steinbigler, R Haberl, J Vogel, I Schmücking, A Spiegl, G Steinbeck

Affiliations

  1. Medizinische Klinik I der Universität München, Marchioninistr. 15, 81366, München.

PMID: 19484327 DOI: 10.1007/BF03042615

Abstract

BACKGROUND: It has not been investigated, whether repeated late potential analysis within 24 hours provides the recognition of functional changes and could be superior to a single analysis.

METHOD: Therefore we performed late potential analysis from the 24 hour Holter-ECG after validation of the method using a standard analysis system (Predictor((R))) and investigated, whether late potential appearance varied over the day and funtional changes were associated with ventricular arrhythmias. Holter tape recordings in 120 post-infarction patients were analyzed. 40 patients had venticular tachycardia (cylce length >230 ms) in the chronic phase after myocardial infarction (VT-group), 40 patients were resuscitated from ventricular fibrillation (VF-group) and 40 patients had no ventricular arrhythmias after myocardial infarction (ØVT/VF-group). The recordings were subdivided in 24 segments of 60min duration. In each segment late potentials in the time domain and the average RR-interval together with its standard deviation (SDNN) were determined.

RESULTS: Investigation with the standard analysis system showed late potentials in 78% of the patients in the VT-group, in 30% in the VF-group and in 15% in the ØVT/VF-group. These late potentials were found analysing the Holter tape recordings in 70% of the VT-group, in 13% of the VF-group and in 5% of the ØVT/VF-group consistently in all 60min-segments. In 85% of the patients of the VF-group, compared to only 20% in the ØVT/VF-group at least in one 60min-segment within the 24hour period late potentials could be found. In patients in the VT-group, only transitory recognizable late potentials were detected predominantly during heart rate accelerations during day time and in phases of reduced heart rate variability.

CONCLUSIONS: Repeated late potential analysis from Holter tape recordings allows the recognition of functional changes and could therefore improve noninvasive risk stratification, particularly of post-infarction patients to ventricular fibrillation.

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