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Opt Express. 2006 Mar 20;14(6):2211-9. doi: 10.1364/oe.14.002211.

Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification.

Optics express

Chad A Lieber, Shiro Urayama, Nazir Rahim, Raymond Tu, Ramez Saroufeem, Boris Reubner, Stavros G Demos

PMID: 19503556 DOI: 10.1364/oe.14.002211

Abstract

We explore nine different combinations of fluorescence, light scattering, and polarization spectral imaging approaches in the near-infrare spectral region toward the diagnosis of pathologic and normal esophageal lesions. The combinations of all the imaging techniques were evaluated for maximal sensitivity and specificity. The results suggest that this multimodal approach is capable of highly accurate detection of the presence of pathologic tissue.

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