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Tob Induc Dis. 2004 Mar 15;2(1):27-33. doi: 10.1186/1617-9625-2-1-27.

Cigarette smoking as a risk factor of coronary artery disease and its effects on platelet function.

Tobacco induced diseases

Teruo Inoue

Affiliations

  1. Department of Cardiology, Koshigaya Hospital, Dokkyo University School of Medicine, Koshigaya, Saitama, Japan. [email protected].

PMID: 19570268 PMCID: PMC2671517 DOI: 10.1186/1617-9625-2-1-27

Abstract

It has been well established that cigarette smoking is a powerful risk factor for coronary artery disease. A number of epidemiologic studies have shown a strong association between cigarette smoking and atherosclerosis, myocardial infarction and death from coronary artery disease. In addition to active smoking, passive smoking can also carry a risk of coronary artery disease. Although the detailed mechanism through which cigarette smoking is associated with cardiovascular disease has not yet been clarified, it is suggested that cigarette smoking is related to thrombogenesis, as well as atherogenesis, and blood platelet behavior is thought to be prominent among the proposed mechanisms involved in atherogenesis and thrombogenesis. The following is a review of evidence that cigarette smoking affects platelet function.

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