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J Org Chem. 2009 Sep 04;74(17):6867-9. doi: 10.1021/jo901310a.

An efficient catalyst system for Pd-catalyzed amination of [2.2]paracyclophanyl bromides.

The Journal of organic chemistry

Bo Qu, Yudao Ma, Qingshuang Ma, Xiao Liu, Fuyan He, Chun Song

Affiliations

  1. Department of Chemistry, Shandong University, Shanda South Road No. 27, Jinan 250100, People's Republic of China.

PMID: 19711999 DOI: 10.1021/jo901310a

Abstract

A practical Buchwald-Hartwig amination of [2.2]paracyclophanyl bromides with benzhydrylideneamine is developed. The method provides a facile route to a variety of imino and amino [2.2]paracyclophanes that are otherwise not readily synthesized.

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