Display options
Share it on

Chemistry. 2009 Sep 28;15(38):9632-6. doi: 10.1002/chem.200901935.

Toward efficient palladium-catalyzed allylic C-H alkylation.

Chemistry (Weinheim an der Bergstrasse, Germany)

Thomas Jensen, Peter Fristrup

Affiliations

  1. Department of Chemistry, Technical University of Denmark, Kemitorvet, building 207, Denmark.

PMID: 19718728 DOI: 10.1002/chem.200901935

Abstract

Recent breakthroughs have proved that direct palladium(II)-catalyzed allylic C-H alkylation can be achieved. This new procedure shows that the inherent requirement for a leaving group in the Tsuji-Trost palladium-catalyzed allylic alkylation can be lifted. These initial reports hold great promise for the development of allylic C-H alkylation into a widely applicable methodology, thus providing a means to enhance synthetic efficiency in these reactions.

Publication Types