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de Sousa JP, Leite MF, Jorge RF, et al. Seasonality Role on the Phenolics from Cultivated Baccharis dracunculifolia. Evid Based Complement Alternat Med. 2011;2011:464289doi: 10.1093/ecam/nep077.
de Sousa, J. P., Leite, M. F., Jorge, R. F., Resende, D. O., da Silva Filho, A. A., Furtado, N. A., Soares, A. E., Spadaro, A. C., de Magalhães, P. M., & Bastos, J. K. (2011). Seasonality Role on the Phenolics from Cultivated Baccharis dracunculifolia. Evidence-based complementary and alternative medicine : eCAM, 2011464289. https://doi.org/10.1093/ecam/nep077
de Sousa, João Paulo B, et al. "Seasonality Role on the Phenolics from Cultivated Baccharis dracunculifolia." Evidence-based complementary and alternative medicine : eCAM vol. 2011 (2011): 464289. doi: https://doi.org/10.1093/ecam/nep077
de Sousa JP, Leite MF, Jorge RF, Resende DO, da Silva Filho AA, Furtado NA, Soares AE, Spadaro AC, de Magalhães PM, Bastos JK. Seasonality Role on the Phenolics from Cultivated Baccharis dracunculifolia. Evid Based Complement Alternat Med. 2011;2011:464289. doi: 10.1093/ecam/nep077. Epub 2011 Jun 23. PMID: 19605554; PMCID: PMC3136527.
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Evid Based Complement Alternat Med. 2011;2011:464289. doi: 10.1093/ecam/nep077. Epub 2011 Jun 23.

Seasonality Role on the Phenolics from Cultivated Baccharis dracunculifolia.

Evidence-based complementary and alternative medicine : eCAM

João Paulo B de Sousa, Mateus F Leite, Renata F Jorge, Dimas O Resende, Ademar A da Silva Filho, Niege A J C Furtado, Ademilson E E Soares, Augusto C C Spadaro, Pedro Melillo de Magalhães, Jairo K Bastos

Affiliations

  1. Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café, s/n, 14040-903, Ribeirão Preto, Brazil.

PMID: 19605554 PMCID: PMC3136527 DOI: 10.1093/ecam/nep077

Abstract

Baccharis dracunculifolia is the source of Brazilian green propolis (BGP). Considering the broad spectrum of biological activities attributed to green proplis, B. dracunculifolia has a great potential for the development of new cosmetic and pharmaceutical products. In this work, the cultivation of 10 different populations of native B. dracunculifolia had been undertaken aiming to determine the role of seasonality on its phenolic compounds. For this purpose, fruits of this plant were collected from populations of 10 different regions, and 100 individuals of each population were cultivated in an experimental area of 1800 m(2). With respect to cultivation, the yields of dry plant, essential oil and crude extract were measured monthly resulting in mean values of 399 ± 80 g, 0.6 ± 0.1% and 20 ± 4%, respectively. The HPLC analysis allowed detecting seven phenolic compounds: caffeic acid, ferulic acid, aromadendrin-4'-methyl ether (AME), isosakuranetin, artepillin C, baccharin and 2-dimethyl-6-carboxyethenyl-2H-1-benzopyran acid, which were the major ones throughout the 1-year monthly analysis. Caffeic acid was detected in all cultivated populations with mean of 4.0%. AME displayed the wide variation in relation to other compounds showing means values of 0.65 ± 0.13% at last quarter. Isosakuranetin and artepillin C showed increasing concentrations with values between 0% and 1.4% and 0% and 1.09%, respectively. The obtained results allow suggesting that the best time for harvesting this plant, in order to obtain good qualitative and quantitative results for these phenolic compounds, is between December and April.

References

  1. J Pharm Pharmacol. 2007 Apr;59(4):603-8 - PubMed
  2. Phytochem Anal. 2009 Jan-Feb;20(1):24-32 - PubMed
  3. Biol Pharm Bull. 2004 Nov;27(11):1834-9 - PubMed
  4. Analyst. 2004 Aug;129(8):739-44 - PubMed
  5. Evid Based Complement Alternat Med. 2005 Mar;2(1):85-92 - PubMed
  6. Z Naturforsch C J Biosci. 2007 Jul-Aug;62(7-8):537-42 - PubMed
  7. Z Naturforsch C J Biosci. 2008 Jan-Feb;63(1-2):40-6 - PubMed
  8. Evid Based Complement Alternat Med. 2008 Sep;5(3):317-24 - PubMed
  9. J Ethnopharmacol. 2008 Dec 8;120(3):372-7 - PubMed
  10. J Ethnopharmacol. 2007 Apr 4;110(3):567-71 - PubMed
  11. J Ethnopharmacol. 2000 Nov;73(1-2):243-9 - PubMed
  12. J Sep Sci. 2007 Nov;30(16):2656-65 - PubMed
  13. Planta Med. 2008 Sep;74(11):1363-7 - PubMed
  14. J Agric Food Chem. 2004 Mar 10;52(5):1100-3 - PubMed
  15. Eur J Pharmacol. 2008 Jun 10;587(1-3):296-301 - PubMed
  16. Evid Based Complement Alternat Med. 2009 Jun;6(2):165-73 - PubMed
  17. Evid Based Complement Alternat Med. 2009 Mar;6(1):113-21 - PubMed
  18. Biol Pharm Bull. 2003 Jul;26(7):1057-9 - PubMed
  19. Evid Based Complement Alternat Med. 2005 Mar;2(1):33-38 - PubMed
  20. Teratog Carcinog Mutagen. 2002;22(3):183-94 - PubMed
  21. Chem Pharm Bull (Tokyo). 2006 Oct;54(10):1465-8 - PubMed
  22. J Ethnopharmacol. 2001 Feb;74(2):105-12 - PubMed
  23. Evid Based Complement Alternat Med. 2011;2011:908743 - PubMed
  24. J Pharm Pharmacol. 2004 Sep;56(9):1195-9 - PubMed
  25. J Pharm Pharmacol. 2007 Mar;59(3):463-8 - PubMed
  26. Evid Based Complement Alternat Med. 2010 Sep;7(3):307-15 - PubMed
  27. J Pharm Biomed Anal. 2006 Sep 26;42(3):354-61 - PubMed

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