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Chem Commun (Camb). 2009 Sep 21;(35):5248-50. doi: 10.1039/b913588j. Epub 2009 Aug 07.

Phosphazene base-catalyzed intramolecular cyclization for efficient synthesis of benzofurans via carbon-carbon bond formation.

Chemical communications (Cambridge, England)

Chikashi Kanazawa, Kengo Goto, Masahiro Terada

Affiliations

  1. Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan.

PMID: 19707635 DOI: 10.1039/b913588j

Abstract

An organic superbase, phosphazene P4-(t)Bu, functioned as an active catalyst for intramolecular cyclization of o-alkynylphenyl ethers via carbon-carbon bond formation to provide an efficient synthetic method for 2,3-disubstituted benzofurans derivatives under mild reaction conditions without the need for a metal catalyst.

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