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Witebsky E, Klendshoj NC. THE ISOLATION OF AN O SPECIFIC SUBSTANCE FROM GASTRIC JUICE OF SECRETORS AND CARBOHYDRATE-LIKE SUBSTANCES FROM GASTRIC JUICE OF NON-SECRETORS. J Exp Med. 1941;73(5):655-67doi: 10.1084/jem.73.5.655.
Witebsky, E., & Klendshoj, N. C. (1941). THE ISOLATION OF AN O SPECIFIC SUBSTANCE FROM GASTRIC JUICE OF SECRETORS AND CARBOHYDRATE-LIKE SUBSTANCES FROM GASTRIC JUICE OF NON-SECRETORS. The Journal of experimental medicine, 73(5), 655-67. https://doi.org/10.1084/jem.73.5.655
Witebsky, E, and Klendshoj, N C. "THE ISOLATION OF AN O SPECIFIC SUBSTANCE FROM GASTRIC JUICE OF SECRETORS AND CARBOHYDRATE-LIKE SUBSTANCES FROM GASTRIC JUICE OF NON-SECRETORS." The Journal of experimental medicine vol. 73,5 (1941): 655-67. doi: https://doi.org/10.1084/jem.73.5.655
Witebsky E, Klendshoj NC. THE ISOLATION OF AN O SPECIFIC SUBSTANCE FROM GASTRIC JUICE OF SECRETORS AND CARBOHYDRATE-LIKE SUBSTANCES FROM GASTRIC JUICE OF NON-SECRETORS. J Exp Med. 1941 Apr 30;73(5):655-67. doi: 10.1084/jem.73.5.655. PMID: 19871103; PMCID: PMC2135150.
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J Exp Med. 1941 Apr 30;73(5):655-67. doi: 10.1084/jem.73.5.655.

THE ISOLATION OF AN O SPECIFIC SUBSTANCE FROM GASTRIC JUICE OF SECRETORS AND CARBOHYDRATE-LIKE SUBSTANCES FROM GASTRIC JUICE OF NON-SECRETORS.

The Journal of experimental medicine

E Witebsky, N C Klendshoj

Affiliations

  1. Laboratories of The Buffalo General Hospital, and the Department of Pathology and Bacteriology, University of Buffalo School of Medicine, Buffalo.

PMID: 19871103 PMCID: PMC2135150 DOI: 10.1084/jem.73.5.655

Abstract

1. The isolation of a group specific O substance from the gastric juice of human beings belonging to group O is described. Absorbed normal beef serum constitutes the anti-O reagent. 2. The O specific substance inhibits the agglutination of human red blood cells belonging to group O. The agglutination of A cells by the isoagglutinin anti-A, or B cells by the isoagglutinin anti-B, is not influenced by the O substance. 3. The A and B specific substances isolated from human gastric juices inhibit the agglutination of O cells by absorbed normal beef serum, frequently to about the same extent as does the O substance itself. 4. The carbohydrate fraction isolated from the gastric juice of non-secretors belonging to group B does not inhibit the agglutination of human red blood cells of group B by the isoagglutinin anti-B nor the agglutination of O cells by the anti-O reagent. The significance of these findings for the conception of the nature of the blood groups and their inheritance is discussed.

References

  1. J Exp Med. 1940 Nov 30;72(6):663-7 - PubMed
  2. J Exp Med. 1938 Jul 31;68(2):221-7 - PubMed
  3. Science. 1932 Oct 14;76(1972):351-2 - PubMed
  4. J Exp Med. 1936 May 31;63(6):813-7 - PubMed
  5. J Exp Med. 1940 Mar 31;71(4):551-62 - PubMed

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