J Gen Physiol. 1918 Nov 20;1(2):181-91. doi: 10.1085/jgp.1.2.181.
The Journal of general physiology
F G Gustafson
PMID: 19871735 PMCID: PMC2140299 DOI: 10.1085/jgp.1.2.181
1. In concentrations which are high enough to produce any effect, formaldehyde, ether, and acetone cause an increase, followed by a decrease, in the rate of respiration. 2. 3.65 per cent ether, which causes an increase with certain cultures, produces only a decrease with others. 3. The reaction producing an increase in the respiration with 7.3 per cent ether is a reversible process, while the reaction producing the decrease is not reversible. 4. 0.5 per cent caffeine produces only a decrease in respiration while a saturated solution causes an increase, which is followed by a decrease.