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Bartlett HL, Weeks DL. Lessons from the lily pad: Using Xenopus to understand heart disease. Drug Discov Today Dis Models. 2008;5(3):141-146doi: 10.1016/j.ddmod.2009.02.006.
Bartlett, H. L., & Weeks, D. L. (2008). Lessons from the lily pad: Using Xenopus to understand heart disease. Drug discovery today. Disease models, 5(3), 141-146. https://doi.org/10.1016/j.ddmod.2009.02.006
Bartlett, Heather L, and Weeks, Daniel L. "Lessons from the lily pad: Using Xenopus to understand heart disease." Drug discovery today. Disease models vol. 5,3 (2008): 141-146. doi: https://doi.org/10.1016/j.ddmod.2009.02.006
Bartlett HL, Weeks DL. Lessons from the lily pad: Using Xenopus to understand heart disease. Drug Discov Today Dis Models. 2008;5(3):141-146. doi: 10.1016/j.ddmod.2009.02.006. PMID: 19802378; PMCID: PMC2747104.
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Drug Discov Today Dis Models. 2008;5(3):141-146. doi: 10.1016/j.ddmod.2009.02.006.

Lessons from the lily pad: Using Xenopus to understand heart disease.

Drug discovery today. Disease models

Heather L Bartlett, Daniel L Weeks

Affiliations

  1. Department of Pediatrics, Roy J. and Lucille Carver College of Medicine, University of Iowa.

PMID: 19802378 PMCID: PMC2747104 DOI: 10.1016/j.ddmod.2009.02.006

Abstract

The developing embryos of the South African (Xenopus laevis) and Western (Xenopus tropicalis) clawed frogs provide an experimentally tractable and easily visualized model for vertebrate cardiovascular development. Most of the genes used to execute the cardiac developmental program are the same in frogs and humans. Experiments using Xenopus provide an underutilized but valuable complement to studies on the molecular, cellular, physiological and morphological consequences of genetic and environmental influences on cardiac disease.

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