Womens Health (Lond). 2007 Sep;3(5):529-35. doi: 10.2217/17455057.3.5.529.
Women's health (London, England)
Anita L Nelson
PMID: 19804029 DOI: 10.2217/17455057.3.5.529
The elimination of monthly withdrawal bleeding with use of extended-cycle (84 pills) monophasic birth-control pills has modernized oral contraceptives. The use of ethinyl estradiol 10 microg pills in place of the seven placebo pills addresses the problems posed by 21/7 formulations of low-dose birth-control pills, which allow early stimulation of ovarian follicles, and of the early 84/7 formulations, which had higher rates of unscheduled bleeding and spotting.