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Pierce A, Miller G, Arden R, et al. Why is intelligence correlated with semen quality?: Biochemical pathways common to sperm and neuron function and their vulnerability to pleiotropic mutations. Commun Integr Biol. 2009;2(5):385-7doi: 10.4161/cib.2.5.8716.
Pierce, A., Miller, G., Arden, R., & Gottfredson, L. S. (2009). Why is intelligence correlated with semen quality?: Biochemical pathways common to sperm and neuron function and their vulnerability to pleiotropic mutations. Communicative & integrative biology, 2(5), 385-7. https://doi.org/10.4161/cib.2.5.8716
Pierce, Arand, et al. "Why is intelligence correlated with semen quality?: Biochemical pathways common to sperm and neuron function and their vulnerability to pleiotropic mutations." Communicative & integrative biology vol. 2,5 (2009): 385-7. doi: https://doi.org/10.4161/cib.2.5.8716
Pierce A, Miller G, Arden R, Gottfredson LS. Why is intelligence correlated with semen quality?: Biochemical pathways common to sperm and neuron function and their vulnerability to pleiotropic mutations. Commun Integr Biol. 2009 Sep;2(5):385-7. doi: 10.4161/cib.2.5.8716. PMID: 19907694; PMCID: PMC2775227.
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Commun Integr Biol. 2009 Sep;2(5):385-7. doi: 10.4161/cib.2.5.8716.

Why is intelligence correlated with semen quality?: Biochemical pathways common to sperm and neuron function and their vulnerability to pleiotropic mutations.

Communicative & integrative biology

Arand Pierce, Geoffrey Miller, Rosalind Arden, Linda S Gottfredson

Affiliations

  1. Department of Pathology; School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA. [email protected]

PMID: 19907694 PMCID: PMC2775227 DOI: 10.4161/cib.2.5.8716

Abstract

We recently found positive correlations between human general intelligence and three key indices of semen quality, and hypothesized that these correlations arise through a phenotype-wide 'general fitness factor' reflecting overall mutation load. In this addendum we consider some of the biochemical pathways that may act as targets for pleiotropic mutations that disrupt both neuron function and sperm function in parallel. We focus especially on the inter-related roles of polyunsaturated fatty acids, exocytosis and receptor signaling.

Keywords: fertility; fitness; intelligence; neuron; semen quality; sperm

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